基于昼夜节律探讨中医学对帕金森病的认识与临床治疗OA

Parkinson's disease(PD)features a protracted course,complex pathology,and a multitude of symptoms,with its pathogeneses yet to be fully elucidated.Circadian rhythm disorder is perceived as a critical pathological factor in PD,which can trigger changes in motor function,sleep,autonomic nervous system activity,and endocrine hormones.The TCM circadian rhythm theory is based on the concept of correspondence between human body and natural environment,with the orderly circulation of nutrient qi and defensive qi as its foundational mechanism.A disharmony between nutrient qi and defensive qi can result in a wide range of symptoms seen in PD.Some approaches in TCM,such as invigorating,activating,and harmonizing nutrient qi and defensive qi,are believed effective in restoring the circadian rhythm and improving the broad spectrum of PD symptoms to a certain extent.