深圳市沿海贝类中二(噁)英富集特征及人群膳食暴露评估研究OA

To reveal the accumulation characteristics of polychlorinated dibenzo-p-dioxins and diben-zofurans(PCDD/Fs)in coastal shellfish from Shenzhen and assess the associated dietary exposure risk for the local population,a total of 79 shellfish samples covering 8 species were collected.17 kinds of PCDD/Fs congeners were determined by isotope dilution high-resolution gas chromatography coupled with high-resolution double-focusing magnetic mass spectrometry(HRGC-HRMS),and an exposure assessment was conducted.The detection rate of PCDD/Fs in all samples was found to be 100％.The total mass concentration ranged from 0.37 to 535 pg/g wet weight,and the total toxic equivalent con-centration(TEQ)ranged from 0.003 9 to 0.55 pg TEQ/g wet weight.The most dominant congener was OCDD,while 1,2,3,7,8-PeCDD contributed the most to the TEQ.In terms of mass con-centration ranking from highest to lowest,it followed the order:clam,mussel,corbicula,pearl shell,scallop,oyster,oriental snail and abalone.In terms of TEQ ranking from highest to lowest,it followed the order:mussel,clam,oyster,oriental snail,pearl shell,corbicula,scallop and abalone.Furthermore,fat content in shellfish samples showed a positive correlation with both PCDD/Fs mass concentration and TEQ.The estimated daily intake of PCDD/Fs from consuming these eight shellfish species was 0.006-0.811 pg WHO-TEQ/kg b.w./day for adult males and 0.007-0.956 pg WHO-TEQ/kg b.w./day for adult females,with median values of 0.136 and 0.161 pg WHO-TEQ/kg b.w./day,respectively.The contamination levels of PCDD/Fs in coastal shellfish from Shenzhen were relatively low,all below the European TEQ limit standards.The total estimated intake of PCDD/Fs from shellfish species for residents was below the permissible maximum tolerable intake level estab-lished by the Joint FAO/WHO Expert Committee on Food Additives.