神经调控技术在脑卒中后失语症治疗中的应用OA

Stroke is one of the leading causes of adult in disability globally,and post-stroke aphasia(PSA),a common neurolog-ical sequela,severely impairs language function and reduces quality of life.With advances in neuroscience,neuromodulation tech-nologies based on the principles of neuroplasticity have emerged as promising therapeutic strategies for PSA.Through invasive or non-invasive interventions,these techniques promote functional reorganization of language networks by modulating synaptic plastic-ity,thereby facilitating language recovery.This review systematically summarizes recent progress in the application of neuromodula-tion technologies for the treatment of PSA.First,it elaborates on the mechanisms underlying language network injury and recovery in PSA,as well as the fundamental principles of neuromodulation.Subsequently,it highlights the clinical applications of mainstream neuromodulation techniques,including transcranial magnetic stimulation(TMS),transcranial electrical stimulation(TES),and brain-computer interface(BCI),and synthesizes existing evidence on their long-term efficacy and safety.Furthermore,the advantages,cur-rent limitations,and future research directions of neuromodulation for PSA are discussed,with the aim of providing a theoretical foundation for optimizing the clinical application of neuromodulation in post-stroke aphasia rehabilitation.