高压氧在老年慢性心力衰竭患者心脏康复中的疗效观察OA

Objective:To investigate the effects of hyperbaric oxygen therapy on cardiopulmonary function and exercise tolerance in elderly patients with chronic heart failure.Methods:A total of 85 elderly patients with chronic heart failure treated in the Department of Cardiac Rehabilitation of Shanghai MC Hospital from February 2023 to September 2024 were selected and divided into a control group(43 cases)and an observation group(42 cases)using the random number table method.Both groups received conventional pharmacological treatment.The control group additionally received cardiac rehabilitation therapy,while the observation group received hyperbaric oxygen therapy in addition to the treatment given to the control group.The following indicators were compared between the two groups before and after treatment:cardiopulmonary reserve function indices including oxygen consumption at the anaerobic threshold(VO2AT),peak oxygen uptake(VO2peak),the ventilatory equivalent for carbon dioxide slope(VE/VCO2 slope),and workload at peak exercise(Load peak);the 6-minute walk test distance(6MWT);cardiac function as measured by left ventricular ejection fraction(LVEF);B-type natriuretic peptide(BNP)levels;hemodynamic indices including stroke volume(SV),cardiac output(CO),cardiac index(CI),and thoracic fluid content(TFC);as well as the incidence of adverse cardiac events during a 6-month follow-up.Results:After treatment,the cardiopulmonary function indices of VO2AT,VO2peak,Load peak,6MWT,LVEF,SV,CO,and CI in both groups were higher than before treatment(P<0.05),while VE/VCO2 slope,BNP,and TFC were lower than before treatment(P<0.05).After treatment,the observation group's cardiopulmonary function indices of VO2AT,VO2peak,Load peak,6MWT,LVEF,SV,CO,and CI were all higher than those of the control group(P<0.05),while the observation group's VE/VCO2 slope,BNP,and TFC were all lower than those of the control group(P<0.05).There was no statistically significant difference in the incidence of adverse cardiac events between the two groups(P>0.05).Conclusion:For elderly patients with chronic heart failure,hyperbaric oxygen therapy should be initiated as early as possible on the basis of conventional drug application and cardiac rehabilitation.This can enhance myocardial contractility,increase cardiac output,improve hemodynamic indicators,improve cardiopulmonary function,increase exercise tolerance,and enhance the safety,compliance and effectiveness of cardiac rehabilitation for patients.