药食同源中药常见活性成分对胃肠道黏膜屏障的保护作用OA

Gastrointestinal mucosal barrier impairment may pose both local and systemic health risks.In addition to the basic safety and nutritional value of conventional foods,Traditional Chinese medicines with both medicinal and food applications contain abundant bioactive compounds,such as polysaccharides,polyphenols,saponins,and alkaloids,which exhibit diverse biological activities,including anti-inflammatory,antioxidant,and immunomodulatory effects.Their ration-al application as dietary ingredients may provide a convenient approach to gastrointestinal mucosal barrier protection in daily life.Based on the literature retrieved from CNKI,PubMed,and other Chinese and international databases,this re-view summarizes the protective effects and underlying mechanisms of the major active components of these TCMs on the gastrointestinal mucosal barrier,and discusses current research challenges and potential solutions,with the aim of provi-ding a reference for the development of functional foods for gastrointestinal protection and the maintenance of gastrointes-tinal health.