首页|期刊导航|中国医学创新|甲钴胺、塞来昔布联合针灸治疗腰椎间盘突出症(肾虚血瘀证)的效果

甲钴胺、塞来昔布联合针灸治疗腰椎间盘突出症(肾虚血瘀证)的效果OA

Efficacy of Mecobalamin,Celecoxib Combined with Acupuncture in the Treatment of Lumbar Disc Herniation(Kidney Deficiency and Blood Stasis Syndrome)

中文摘要英文摘要

目的:探讨甲钴胺、塞来昔布联合针灸治疗腰椎间盘突出症(肾虚血瘀证)的效果.方法:选择 2023 年 6 月—2025 年 6 月于厦门大学附属第一医院接受治疗的 98 例腰椎间盘突出症(肾虚血瘀证)患者,按照 1∶1 随机分成对照组(甲钴胺+塞来昔布治疗)、试验组(在对照组基础上联合针灸治疗),各 49 例.连续治疗 14 d.比较两组的中医证候积分、腰椎功能[Oswestry 功能障碍指数(ODI)评分、日本骨科学会(JOA)腰椎评分]、疼痛状况[简版麦吉尔疼痛问卷(SF-MPQ)评分]、炎症因子(TNF-α、IL-1、IL-6).结果:治疗后,与对照组相比,试验组各项中医证候积分、ODI 评分、各项 SF-MPQ 评分更低,JOA 腰椎评分更高(P<0.05);治疗后,试验组 TNF-α、IL-1、IL-6 较对照组低(P<0.05).结论:甲钴胺联合塞来昔布并配合针灸治疗腰椎间盘突出症(肾虚血瘀证)能够改善临床症状,促进腰椎功能恢复,减轻疼痛程度并抑制炎症反应.

Objective:To explore the effect of Mecobalamin,Celecoxib combined with acupuncture in the treatment of lumbar disc herniation(kidney deficiency and blood stasis syndrome).Method:A total of 98 patients with lumbar disc herniation(kidney deficiency and blood stasis syndrome)who were treated at the First Affiliated Hospital of Xiamen University from June 2023 to June 2025 were selected and randomly divided into control group(treated with Mecobalamin+Celecoxib)and experimental group(treated with acupuncture on the basis of the control group)in a 1:1 ratio,with 49 cases in each group.Continuous treatment for 14 days.The traditional Chinese medicine syndrome scores,lumbar spine functions[Oswestry disability index(ODI)score,Japanese Orthopaedic Association(JOA)lumbar spine score],pain conditions[short form McGill pain questionnaire(SF-MPQ)score],and inflammatory factors(TNF-α,IL-1,IL-6)of the two groups were compared.Result:After treatment,compared with the control group,the scores of various traditional Chinese medicine syndromes,ODI scores,and various SF-MPQ scores in the experimental group were lower,while the JOA lumbar spine score was higher(P<0.05).After treatment,the levels of TNF-α,IL-1 and IL-6 in the experimental group were lower than those in the control group(P<0.05).Conclusion:Mecobalamin,Celecoxib combined with acupuncture can improve clinical symptoms,promote recovery of lumbar function,alleviate pain,and suppress inflammatory responses in the treatment of lumbar disc herniation(kidney deficiency and blood stasis syndrome).

郑显达;徐锐

厦门大学附属第一医院中西医结合骨伤科 福建 厦门 361003厦门大学附属第一医院中医科 福建 厦门 361003

医药卫生

甲钴胺塞来昔布针灸腰椎间盘突出症中医证候积分炎症因子

MecobalaminCelecoxibAcupunctureLumbar disc herniationTraditional Chinese medicine syndrome scoreInflammatory factors

《中国医学创新》 2026 (24)

53-57,5

10.3969/j.issn.1674-4985.2026.24.013

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