肝脾同调(逍遥散合归脾汤加减)联合中药香囊治疗慢性紧张型头痛的临床研究OA
Clinical Study on Liver-Spleen Coregulation(Modified Xiaoyao Powder and Guipi Decoction)Combined with Chinese Herbal Sachet in the Treatment of Chronic Tension-type Headache
目的:探讨肝脾同调(逍遥散合归脾汤加减)联合中药香囊治疗慢性紧张型头痛(肝郁脾虚证)的临床效果.方法:采用随机对照试验设计,选取 2024 年 8 月—2026 年 1 月在阳江市中医医院脑病科就诊的慢性紧张型头痛(肝郁脾虚证)患者 70 例作为研究对象,基于随机数字表法分为对照组与治疗组,各 35 例.对照组予以布洛芬缓释胶囊联合氟哌噻吨美利曲辛片的西医常规治疗,治疗组予逍遥散合归脾汤加减口服,并配合中药香囊.两组疗程均为 4 周.记录比较两组治疗前后疼痛程度、中医证候积分,并于治疗后评价疗效与安全性.结果:治疗后,治疗组头痛发作次数少于对照组,单次最长发作时间短于对照组,数字分级评分法(NRS)评分低于对照组(P<0.05).治疗后,治疗组主症、次症积分及中医证候总积分低于对照组(P<0.05).治疗组头痛总有效率(94.29%)、中医证候总有效率(88.57%)高于对照组(77.14%、62.86%)(P<0.05).两组均未报告严重消化道症状、神经系统症状、锥体外系症状.结论:肝脾同调(逍遥散合归脾汤加减)联合中药香囊治疗慢性紧张型头痛(肝郁脾虚证)的效果确切,能够有效减轻疼痛,改善中医证候,且安全性高.
Objective:To explore the clinical efficacy of liver-spleen coregulation(modified Xiaoyao Powder and Guipi Decoction)combined with Chinese herbal sachet in the treatment of chronic tension-type headache(liver stagnation and spleen deficiency syndrome).Method:A randomized controlled trial design was used,70 patients with chronic tension-type headache(liver stagnation and spleen deficiency syndrome)who visited the Department of Encephalopathy,Yangjiang Hospital of Traditional Chinese Medicine from August 2024 to January 2026 were selected as the research subjects.According to the random number table method,they were divided into the control group and the treatment group,with 35 cases in each group.The control group was treated with conventional western medicine therapy consisting of Ibuprofen Sustained Release Capsules combined with Flupentixol and Melitracen Tablets,the treatment group was given oral administration of modified Xiaoyao Powder and Guipi Decoction,combined with Chinese herbal sachet.The two groups were treated for 4 weeks.The pain degree and traditional Chinese medicine syndromes scores were recorded and compared between the two groups before and after treatment,and the efficacy and safety were evaluated after treatment.Result:After treatment,the number of headache episodes in the treatment group was less than that in the control group,and the longest single episode duration was shorter than that in the control group,the numerical rating scale(NRS)score was lower than that in the control group(P<0.05).After treatment,the main symptom scores,secondary symptom scores,and the total scores of traditional Chinese medicine syndromes in the treatment group were lower than those in the control group(P<0.05).The total effective rate of headache(94.29%)and the total effective rate of traditional Chinese medicine syndromes(88.57%)in the treatment group were higher than those in the control group(77.14%and 62.86%)(P<0.05).Neither of the two groups reported severe digestive tract symptoms,neurological symptoms,or extrapyramidal symptoms.Conclusion:Liver-spleen coregulation(modified Xiaoyao Powder and Guipi Decoction)combined with Chinese herbal sachet in the treatment of chronic tension-type headache(liver stagnation and spleen deficiency syndrome)is effective,it can effectively reducing pain,improving traditional Chinese medicine syndromes,and has high safety.
杨琼;冯国忠;黄益好
阳江市中医医院脑病科 广东 阳江 529500阳江市中医医院脑病科 广东 阳江 529500阳江市中医医院脑病科 广东 阳江 529500
医药卫生
慢性紧张型头痛肝郁脾虚证肝脾同调布洛芬缓释胶囊氟哌噻吨美利曲辛片中药香囊
Chronic tension-type headacheLiver stagnation and spleen deficiency syndromeLiver-spleen coregulationIbuprofen Sustained Release CapsulesFlupentixol and Melitracen TabletsChinese herbal sachet
《中国医学创新》 2026 (23)
132-136,5
阳江市医疗卫生科技计划项目(SF2024029)
评论