肺癌术后声音嘶哑的病因、评估与综合管理OA
Etiology,Evaluation and Comprehensive Management of Hoarseness after Lung Cancer Surgery
肺癌术后声音嘶哑是胸外科常见但易被低估的围手术期功能性并发症.其不仅影响发声质量,还可能累及吞咽与气道保护功能,从而增加误吸、肺部感染及康复延迟风险.医源性喉返神经损伤是主要病因,且与纵隔淋巴结清扫密切关联;其中左下气管旁淋巴结区域为典型高危解剖区.喉返神经损伤既可由直接机械性损害引起,也可因牵拉与热损伤等间接因素导致神经功能障碍.与此同时,气管插管相关喉部机械性损伤亦可表现为术后声音嘶哑,需与神经源性病因鉴别.本文总结病因谱与危险因素,并概述术后评估要点与预防策略,包括精细解剖、减少热损伤及合理使用术中神经监测.未来研究应推动前瞻性与标准化证据,以明确不同干预的最佳时机与适用人群,并完善胸外科综合管理路径,提升患者术后生活质量.
Hoarseness after lung cancer surgery is a common but often underestimated perioperative functional complication.Beyond impairing voice quality,it may involve swallowing dysfunction and compromised airway protection,thereby increasing the risk of aspiration,pulmonary infection,and delayed recovery.Iatrogenic recurrent laryngeal nerve injury is the major cause,closely associated with mediastinal lymph node dissection,with the leftlower paratracheal lymph node sta-tion as typical high-risk anatomical areas.Nerve injury results from both direct mechanical trauma and indirect mechanisms such as traction and thermal spread.In addition,intubation-related laryngeal trauma can also present as postoperative hoarse-ness and should be differentiated from neurogenic causes.This review summarizes the etiology and risk factors,outlines post-operative evaluation and preventive strategies,and discusses the role of meticulous dissection,minimized thermal injury,and appropriate intraoperative neuromonitoring.Future prospective studies are needed to standardize outcomes and clarify the optimal timing and target populations for interventions,ultimately improving comprehensive perioperative management and patients'quality of life.
门鹏飞;梁甲林;张锋;王晓龙
475000 开封,河南大学第二临床学院475000 开封,河南大学第二临床学院河南大学淮河医院胸外科河南大学淮河医院胸外科
肺肿瘤声音嘶哑喉返神经损伤声带麻痹纵隔淋巴结清扫综合管理
Lung neoplasmsHoarsenessRecurrent laryngeal nerve injuryVocal fold paralysisMediastinal lymph node dissectionComprehensive management
《中国肺癌杂志》 2026 (7)
533-539,7
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