噬菌体内溶素的特性及其在动物生产中的应用OA

As a natural protein that can specifically hydrolyze bacterial peptidoglycan,phage endolysin has shown great potential in the field of animal husbandry due to its efficient and broad-spectrum lytic activity,low risk of inducing drug resistance,low immunogenicity,and residue-free characteristics,as well as its biological functions including immunomodulation,antitumor activity,and antioxidant effects.This article reviews the molecular structure,mechanism of action,and biological functions of phage endolysins,with a focus on their application effects in pigs,chickens,cattle,and aquatic animals.It also discusses the application prospects and challenges of phage endolysins,aiming to provide a reference for their use as feed additives in animal production.