山楂叶总黄酮对肉鸡生长性能、抗氧化功能及肠道健康的影响OA

The experiment aimed to investigate the effects of total flavonoids from hawthorn leaves(TFHL)on the growth performance,antioxidant function,and intestinal health of broilers.A total of 240 AA broilers aged one day were randomly divided into six groups with five replicates per group and eight broilers per replicate.The control group(group CON)was fed a basal diet,the group EQ was fed the basal diet supplemented with 150 mg/kg ethoxyquin(EQ),the group VE was fed the basal diet supplemented with 150 mg/kg vitamin E(VE),and the groups TFHL-L,TFHL-M,and TFHL-H were fed the basal diet supplemented with 250,500,and 750 mg/kg TFHL,respectively.The pre-test period lasted seven days,and the formal trial lasted 42 days.The results showed that compared with the group CON,the average daily gain(ADG)of the groups TFHL-M and TFHL-H at 1 to 42 days of age significantly increased by 6.33%and 6.04%,respectively(P<0.05),and the feed-to-gain ratio(F/G)was significantly decreased(P<0.05).The ADG of the groups TFHL-M and TFHL-H was significantly higher than that of the group EQ(P<0.05).The total antioxidant capacity(T-AOC),total superoxide dismutase(T-SOD)activity,and glutathione peroxidase(GSH-Px)activity in the serum and liver of groups TFHL-M and TFHL-H were significantly increased(P<0.05),while the content of malondialdehyde(MDA)was significantly decreased(P<0.05).The levels of serum interleukin-1β(IL-1β),interleukin-6(IL-6),and tumor necrosis factor-α(TNF-α)were significantly reduced(P<0.05).The MDA content in the duodenal and jejunal mucosa was significantly reduced(P<0.05),while the T-SOD activity and chyme trypsin and amylase activities were significantly increased(P<0.05).The study shows that dietary supplementation with TFHL can promote growth performance,enhance antioxidant function,and improve intestinal health in broilers,with 500 mg/kg being the appropriate supplemental level.