首页|期刊导航|北京中医药大学学报|"土枢四象"理论视域下抑郁症的病机与辨治探析

"土枢四象"理论视域下抑郁症的病机与辨治探析OA

Exploring the pathogenesis,syndrome differentiation,and treatment of depression from the theory of"earth as pivot with four elements"

中文摘要英文摘要

"土枢四象"理论以脾胃为人体气机运转之枢,强调脾升清阳以助水木左升,胃降浊阴而引火金右降,由此推动气血周流,维系阴阳平衡,使五脏调和、神志得安.基于此理论体系,探析抑郁症之病机核心可能在于中焦枢机不利,气机升降失常.初起多因脾不升清致肝木郁滞,气郁神萎;继而胃失和降,浊阴上扰,气逆神乱;若迁延不愈,则枢轴滞塞,寒热错杂,一气周流受阻,神机惑乱,而成难解之局.治疗应以恢复中焦升降、调畅一气周流为主.初期宜温运中焦,调中启神,方选香砂六君子汤佐以柴胡、白芍以调达气机;发展期当和胃导浊,降逆安神,主以温胆汤加减;若病至迁延,呈现上热下寒、心肾不交之候,则可投半夏泻心汤合交泰丸加减,寒热并调、交通心肾.此法思路皆以运转中土、复其升降为要,使四象归位,周流复常,为抑郁症的审机论治提供系统思路与理论参考.

The"earth as pivot with four elements"theory posits the spleen and stomach as the pivot governing systemic qi dynamics.It emphasizes the physiological interdependence wherein the spleen elevates clear yang to facilitate the leftward ascent of water and wood,whereas the stomach descends the turbid yin to guide the rightward descent of fire and metal.This mechanism sustains the cyclical flow of qi and blood,preserves yin-yang balance,harmonizes the five zang organs,and stabilizes the spirit.Within this theoretical framework,the core pathogenesis of depression is identified as middle jiao pivot dysfunction and derangement of qi ascending-descending movement.The initial stage is characterized by the spleen failing to elevate clear yang,leading to the constraint and sinking of liver-wood,which manifests as qi stagnation and mental lassitude.This progresses to the stomach,which fails to descend turbidity,allowing phlegm-turbidity to harass the spirit and cause spiritual disorientation.In chronic refractory cases,pivot obstruction results in an intermingling of cold and heat,blocking the qi circle in round and inducing a state of profound spirit disturbance,and it becomes a difficult and intractable situation.Therapeutically,the primary objective is to restore the ascending-descending function of the middle jiao and regulate the cyclical flow of qi.In the early stage,it should warm and activate the middle jiao to awaken the spirit,using Xiangsha Liujunzi Decoction accompanied by Chaihu(Bupleuri Radix)and Baishao(Paeoniae Radix Alba)to regulate qi movement.In the progressive stage,prioritize harmonizing the stomach and guiding turbidity to calm the spirit by using modified Wendan Decoction.In the chronic stage,address the syndrome of upper heat and lower cold with heart-kidney non-interaction with modified Banxia Xiexin Decoction combined with Jiaotai Pill,to balance cold and heat and harmonize the heart and kidney.This approach highlights the restoration of spleen-stomach rotation and its ascending and descending as the key method to reposition the four elements and re-establish physiological qi circulation,offering a systematic theoretical reference for the syndrome differentiation and treatment of depression.

徐文琪;王晓鸽;刘佳;许二平

河南中医药大学第一附属医院脾胃肝胆科 郑州 450003||河南中医药大学第一临床医学院河南中医药大学第一附属医院脾胃肝胆科 郑州 450003河南中医药大学第一附属医院脾胃肝胆科 郑州 450003河南中医药大学||河南省豫药全产业链研发河南省协同创新中心

医药卫生

抑郁症土枢四象脾胃气机神

depressionearth as pivot with four elementsspleen and stomachqi movementspirit

《北京中医药大学学报》 2026 (8)

1124-1129,6

国家自然科学基金项目(No.82274496,No.82104776)河南省科技研发计划联合基金(优势学科培养类)重点项目(No.222301420021)河南中医药大学张仲景传承与创新专项(No.GZY-KJS-2022-044-1) National Natural Science Foundation of China(Nos.82274496 and 82104776)

10.3969/j.issn.1006-2157.2026.08.010

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