癌症一级预防核心知识知晓问卷的开发与验证:一项Delphi与网络应答驱动抽样研究OA

Background Nearly half of all cancers can be prevented through primary prevention methods,and standardized questionnaires to assess knowledge and awareness of primary cancer prevention are essential for evaluating the effectiveness of prevention implementation.There is therefore a need to develop evidence-based recommendations to guide people in reducing their exposure to cancer risk factors.Objective This study aimed to develop and validate a standardized questionnaire to assess knowledge and awareness of primary cancer prevention,based on the China Code Against Cancer(CCAC).Methods Two cross-sectional surveys were conducted from May to October 2024.The questionnaire was developed and refined through a two-round Delphi process(n=34),followed by a pilot study using convenience sampling(n=344),and a web-based respondent-driven sampling(RDS)survey(n=571).The reliability of the Delphi consensus was evaluated using response rates,credibility coefficients,and Kendall's coefficient of concordance(Kendall's W).The final questionnaire's reliability and structural validity were assessed using Cronbach's α,McDonald's ω,and confirmatory factor analysis.Results The expert response rates in the two Delphi rounds were 95.83%and 100.00%,with credibility coefficients of 0.894 and 0.912,and Kendall's W values of 0.148 and 0.097,respectively(both P<0.001),indicating strong expert consensus.Based on expert feedback and empirical analysis,a final questionnaire comprising 34 items across two dimensions(knowledge and belief)was developed.The internal consistency was high,with Cronbach's α=0.874 and McDonald's ω=0.905.Confirmatory factor analysis indicated good model fit.Conclusion We successfully developed and validated a standardized questionnaire for assessing knowledge and awareness of primary cancer prevention based on CCAC.This tool provides a scientific basis for evaluating cancer prevention education efforts and promoting evidence-based health communication strategies.