加工方式对天麻酚类活性成分的影响及其机制研究进展OA
Effects of Processing Methods on Active Components in Gastrodia elata and Their Mechanisms:A Review
天麻(Gastrodia elata)作为药食同源中药材,其富含的酚类成分(如天麻素、巴利森苷类)是发挥神经保护等药理作用的关键物质基础,而采后加工是决定其最终品质的核心环节.本文系统综述蒸制、干燥等加工过程中天麻主要活性成分,特别是酚类物质的动态转化规律与机制,阐明热诱导转化与内源酶调控是驱动其成分变化的主要途径.通过比较传统与现代加工技术(如高温高压、红外、热泵及联合干燥等)对活性成分保留、微观结构及综合品质的影响,分析当前研究在完整转化网络解析与体内功效关联验证方面的不足.在此基础上,对应用多组学技术与智能模型实现天麻加工精准工艺设计的未来方向进行展望,以期为最大限度保留天麻活性成分、提升其资源利用价值提供理论依据.
Gastrodia elata,a traditional Chinese medicinal and culinary herb,owes its key pharmacological activities,such as neuroprotection,primarily to its rich phenolic constituents(e.g.,gastrodin and parishins).Post-harvest processing is a crucial stage that determines its final quality.This review systematically summarizes the dynamic transformation patterns and underlying mechanisms of the major active ingredients of G.elata,especially phenolic compounds,during processing steps like steaming and drying.It highlights that heat-induced conversion and endogenous enzyme regulation are the principal pathways driving these compositional changes.By comparing the effects of traditional and modern processing techniques(e.g.,high-temperature/high-pressure steaming,infrared drying,heat pump drying,and combined drying methods)on the retention of active ingredients,microstructure,and overall quality,the review identifies current research gaps,including insufficient understanding of the complete transformation networks and a lack of validation of in vivo efficacy.Furthermore,it outlines future research directions involving the application of multi-omics technologies and intelligent modeling for precision process design.The aim is to provide a theoretical foundation for maximizing the retention of active ingredients in G.elata and enhancing its resource utilization value.
冉云诗;刘洁妮;刘大会;乔宇;张莉会
湖北中医药大学药学院,湖北 武汉 430065湖北中医药大学药学院,湖北 武汉 430065湖北中医药大学药学院,湖北 武汉 430065||湖北时珍实验室,湖北 武汉 430065湖北省农业科学院农产品加工与核农技术研究所,湖北 武汉 430064湖北中医药大学药学院,湖北 武汉 430065||湖北时珍实验室,湖北 武汉 430065
医药卫生
天麻酚类成分加工方式蒸制干燥
Gastrodia elataphenolic constituentsprocessing methodssteamingdrying
《食品科学》 2026 (17)
369-377,9
湖北省自然科学基金项目(2026AFB215)"十四五"国家重点研发计划项目(2023YFC3503804)湖北省科技计划项目(2025BCA007)湖北省支持种业高质量发展资金项目(HBZY2023B00503)湖北省中医药管理局创新团队项目(ZY2025J002)2024年湖北省中药材产业链扶持资金项目
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