基于体外消化模型的饲料添加生物炭对全氟辛烷磺酸生物有效性的影响OA

The regulatory effects of three types of biochar(wood chip biochar,coconut shell biochar,and bamboo biochar)as feed additives on the bioavailability of perfluorooctane sulfonate(PFOS)were evaluated using an in vitro digestion(IVD)model.Meanwhile,linear fitting and correlation analysis were employed to explore the correlation between biochar dosage and PFOS bioavailability.The results showed that the PFOS bioavailability in the basal feed(no biochar supplementation control)was 45.08％.When the biochar addition rate was 5％(mass fraction),the PFOS bioavailability in the feeds supplemented with the three biochars ranged from 27.40％to 41.02％,all lower than that of the control,indicating that biochar supplementation in feed could reduce PFOS bioavailability.The regulatory effect of biochar exhibited a dose-dependent pattern and was closely related to biochar type.Specifically,the dosage of coconut shell biochar showed a significant negative correlation with PFOS bioavailability(R2=0.449 2).The bamboo biochar and wood chip biochar presented no significant dose-dependent relationship.Collectively,coconut shell biochar can serve as a low-cost and eco-friendly feed additive to reduce PFOS bioavailability and further reduce PFOS accumulation in animals,thereby providing a novel strategy for pollutant control in animal husbandry.