老年人cMIND饮食轨迹与认知功能的关联性研究OACHSSCD

Cognitive impairment poses a major public health challenge in aging societies,and dietary nutrition is considered a key modifiable target.The China-adapted MIND(cMIND)diet has been preliminarily established,but longitudinal evidence supporting its association with cognitive impairment among older adults remains limited.This study focused on Chinese older adults aged≥65 years and used four waves of data(2008-2018)from the Chinese Longitudinal Healthy Longevity Survey(CLHLS)to identify long-term trajectories of cMIND diet adherence through latent class growth analysis and examine their relationship with cognitive impairment.Results showed that cMIND diet adherence among older adults followed four distinct trajectories:persistently high,stable moderate,moderate-declining,and persistently low.Compared with the persistently high adherence group,the risk of cognitive impairment was 35％higher in the moderate-declining group,and 48％higher in the persistently low group(both P<0.05).Advanced age,educational level below elementary school,rural residence,lack of regular physical exercise,and depression were independent risk factors for low-adherence trajectories.Maintaining long-term high adherence to the cMIND diet,rather than focusing solely on one-time intake,is an important modifiable target for preventing cognitive impairment among older adults.Community-based nutritional interventions should be initiated early and sustained over the long-term,with particular attention to vulnerable populations,including rural residents and those with low educational levels.