AI-aided design of multi-epitope peptide vaccine elicits cellular and humoral immunity to broad Omicron subvariantsOA
AI-aided design of multi-epitope peptide vaccine elicits cellular and humoral immunity to broad Omicron subvariants
Kai Zhang;Xinxin Zhang;Jing Chen;Guangyu Zhao;Xingchao Geng;Yiru Long;Likun Gong;Gangao Wang;Tingting Liu;Min Li;Longfei Ding;Yanqi Zhao;Jianqing Xu;Honglin Li;Jianhua Sun
School of Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing,Jiangsu 210023,China||State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,ChinaShandong Laboratory of Yantai Drug Discovery,Bohai Rim Advanced Research Institute for Drug Discovery,Yantai,Shandong 264117,ChinaSchool of Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing,Jiangsu 210023,China||State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,ChinaState Key Laboratory of Pathogen and Biosecurity,Academy of Military Medical Sciences,Beijing 100071,ChinaInstitute for Biological Product Control,National Institutes for Food and Drug Control,Beijing 100176,ChinaState Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,ChinaSchool of Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing,Jiangsu 210023,China||State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China||Zhongshan Institute for Drug Discovery,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Zhongshan,Guangdong 528400,ChinaInnovation Center for AI and Drug Discovery,School of Pharmacy,East China Normal University,Shanghai 200062,ChinaState Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,ChinaState Key Laboratory of Pathogen and Biosecurity,Academy of Military Medical Sciences,Beijing 100071,ChinaShanghai Public Health Clinical Center & Institutes of Biomedical Sciences,Fudan University,Shanghai 201508,ChinaShandong Laboratory of Yantai Drug Discovery,Bohai Rim Advanced Research Institute for Drug Discovery,Yantai,Shandong 264117,ChinaShanghai Public Health Clinical Center & Institutes of Biomedical Sciences,Fudan University,Shanghai 201508,ChinaInnovation Center for AI and Drug Discovery,School of Pharmacy,East China Normal University,Shanghai 200062,ChinaState Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China||Zhongshan Institute for Drug Discovery,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Zhongshan,Guangdong 528400,China
Peptide vaccineAI-aided designSARS-CoV-2T-and B-cell epitopes
Peptide vaccineAI-aided designSARS-CoV-2T-and B-cell epitopes
《动物学研究》 2026 (3)
851-865,15
This work was supported by the Strategic Priority Research Program,Chinese Academy of Sciences(XDB1310302),National Key Research and Development Program of China(2022YFC2304105),National Natural Science Foundation of China(82341039),Postdoctoral Fellowship Program of CPSF(GZB20230797),and Zhongshan Municipal Bureau of Science and Technology(CXTD2023010)
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