首页|期刊导航|中华中医药学刊|基于浊毒理论探讨自稳态失衡与慢性萎缩性胃炎的关系

基于浊毒理论探讨自稳态失衡与慢性萎缩性胃炎的关系OA

Discussion on Relationship Between Homeostasis and Chronic Atrophic Gastritis Based on Turbid Toxicity Theory

中文摘要英文摘要

浊毒蕴胃致机体自稳态失衡是导致慢性萎缩性胃炎的重要致病机制之一.国医大师李佃贵教授提出浊毒理论,并系统阐述了浊毒的内涵、物质形态以及浊毒的形成原因.化浊解毒法是李佃贵教授提出治疗慢性萎缩性胃炎浊毒蕴胃证的大法,同时也是调节机体自稳态使其平衡的重要环节.浊毒理论的核心是净化人体内环境,和其不和,使人体由浊毒状态恢复至清净状态.慢性萎缩性胃炎患者处于浊毒蕴胃的状态会导致机体出现气、血、阴、阳失调,进而影响脏腑功能.这也与浊毒致病后慢性萎缩性胃炎"炎-癌转化"的病机演变过程相符.机体内的气血阴阳失调与机体自稳态失衡相对应,进而导致脏腑功能失调或"炎-癌转化"的进一步发展.通过自稳态失衡的理论来阐述浊毒致病,不仅拓宽了慢性萎缩性胃炎"炎-癌转化"新释义,而且为临床上治疗慢性萎缩性胃炎提供了新的思路.

The homeostasis imbalance caused by turbidity-toxicity in the stomach is one of the important pathogenic mecha-nisms leading to chronic atrophic gastritis.Professor LI Diogui,a master of traditional Chinese medicine,has put forward the theo-ry of turbidity-toxicity,and systematically expounds the connotation,material form and the formation reason of turbidity-toxici-ty.The method of eliminating turbidity and detoxifying is a great method proposed by Master LI to treat the syndrome of turbidity-toxicity in the stomach of chronic atrophic gastritis,and it is also an important link to adjust the homeostasis of the body to make it balance.The core of the theory of turbidity-toxicity is to purify the environment in the human body and harmo-nize the disharmony of the body,so that the human body can recover from the state of turbidity-toxicity to a pure state.The pa-tients with chronic atrophic gastritis are in the state of turbidity-toxicity in the stomach,which will lead to the imbalance of Qi,blood,Yin and Yang in the body,and then affect the function of Zang-Fu organs.This is also consistent with the pathogenesis of chronic atrophic gastritis after"inflammation-cancer transformation".The imbalance of Qi,blood and Yin and Yang in the body corresponds to the imbalance of body homeostasis,which leads to the further development of Zang-Fu organs dysfunction or"in-flammation-cancer transformation".Through the theory of homeostasis imbalance to explain the turbidity-toxicity of chronic a-trophic gastritis,it not only broadens the new definition of"inflammation-cancer transformation",but also provides a new idea for clinical treatment of chronic atrophic gastritis.

王绍坡;王玉曼;王孟超;孙润雪;马晓菲;杨柳;刘致尧;姜冲;杜艳茹

河北省中医院,河北石家庄 050011河北中医药大学研究生学院,河北石家庄 050091天津中医药大学第一附属医院,天津 300380河北省中医院,河北石家庄 050011河北省中医院,河北石家庄 050011河北中医药大学研究生学院,河北石家庄 050091河北中医药大学研究生学院,河北石家庄 050091山东中医药大学,山东济南 250355河北省中医院,河北石家庄 050011

医药卫生

浊毒慢性萎缩性胃炎自稳态失衡

turbidity-toxicitychronic atrophic gastritishomeostasis

《中华中医药学刊》 2026 (8)

41-44,4

国家中医药管理局科技项目(GZY-KJS-2023-013)国家中医药管理局第三届国医大师传承工作室建设项目(国中医药办人教函[2018]119号)河北省重点研发计划项目(23377701D)河北省中医药管理局项目(2024236)

10.13193/j.issn.1673-7717.2026.08.009

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