基于COM-B模型的痛风患者服药依从性促进与阻碍因素质性研究OA

Objective To understand the authentic medication experiences and perceptions of patients with gout,explore the facilitating factors and barriers affecting medication adherence.Methods A total of 16 patients with gout who were hospitalized in the Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine/Guizhou Provincial Hospital of Integrated Traditional Chinese and Western Medicine from June to September 2025 were selected for in-depth interviews.The interview data were analyzed,and themes were extracted based on the capability,opportunity,motivation-behavior(COM-B)model as the theoretical framework.Results Seven sub-themes related to barriers were identified:Insufficient disease and medication knowledge,adverse drug reactions,reduced patient capability,inadequate social support,poor economic conditions and high costs of accessing medical resources,low medication adherence confidence,and low perceived medication benefits.Four sub-themes related to facilitating factors were identified:Structured medication habits,adequate social support,patient-physician trust and treatment confidence,and disease severity with perceived consequences.Conclusion The factors influencing medication adherence in patients with gout are multidimensional.Healthcare professionals should provide personalized health education tailored to the specific reasons for poor medication adherence in individual patients.