远隔缺血适应训练改善老年轻型缺血性卒中患者衰弱及焦虑抑郁的研究OA

Objective To investigate the effect of remote ischemic conditioning training on frailty,anxiety and depression in elderly patients with mild ischemic stroke. Methods This prospective study consecutively enrolled elderly patients with mild ischemic stroke who were treated in the Department of Neurology,North China University of Science and Technology Affiliated Hospital from March 2024 to February 2025.The control group received routine nursing care and rehabilitation therapy,while the experimental group received remote ischemic conditioning training in addition to routine treatment.The frail scale(FRAIL)score,muscle strength,self-rating anxiety scale(SAS)score,self-rating depression scale(SDS)score,stroke-specific quality of life scale(SS-QOL)score were compared between the two groups on day 14 and 90 after intervention. Results A total of 99 elderly patients with mild ischemic stroke were included,with 50 in the control group and 49 in the experimental group.On day 14 and 90 after intervention,the FRAIL scale scores in the experimental group were significantly lower than those in the control group(|Z|≥3.174,all P<0.01),and muscle strength was significantly higher(|Z|≥2.733,all P<0.01).On day 90 after intervention,the SAS score(t=4.147,P<0.001)and SDS score(t=3.327,P=0.001)in the experimental group were significantly lower than those in the control group,and the SS-QOL score in the experimental group was significantly higher than that in the control group(|Z|=3.721,P<0.001). Conclusions Remote ischemic conditioning training is beneficial for improving frailty,enhancing muscle strength,alleviating anxiety and depression,and improving quality of life in elderly patients with mild ischemic stroke.