首页|期刊导航|中国医学创新|缩泉丸加味联合乳果糖治疗肾阳虚型便秘患者的效果

缩泉丸加味联合乳果糖治疗肾阳虚型便秘患者的效果OA

Efficacy of Modified Suoquan Pills Combined with Lactulose in the Treatment of Constipation Patients with Kidney-Yang Deficiency Type

中文摘要英文摘要

目的:探讨缩泉丸加味联合乳果糖治疗肾阳虚型便秘患者的临床效果.方法:选取 2024 年12 月—2025 年 8 月赣州市中医院收治的 80 例肾阳虚型便秘患者,按随机数字表法分组,各 40 例.两组均接受常规基础治疗,对照组加用乳果糖治疗,观察组在对照组基础上加用缩泉丸加味治疗,均连续治疗 4 个周期(每周期 7 d).比较两组治疗前后中医证候积分、临床症状(排便次数、每次排便时长、大便性状)及不良反应发生率.结果:治疗后,观察组大便干结、排便费力、畏寒肢冷、腰膝酸软积分及总分均低于对照组,排便次数多于对照组,每次排便时长短于对照组,大便性状优于对照组,治疗期间不良反应发生率低于对照组(P<0.05).结论:缩泉丸加味联合乳果糖可有效改善肾阳虚型便秘患者中医证候及临床症状,降低不良反应发生率,安全性较高.

Objective:To investigate the clinical efficacy of modified Suoquan Pills combined with Lactulose in the treatment of patients with constipation of kidney-Yang deficiency type.Method:A total of 80 patients with constipation of kidney-Yang deficiency type admitted to Ganzhou Traditional Chinese Medicine Hospital from December 2024 to August 2025 were selected and divided into two groups according to the random number table method,with 40 cases in each group.Both groups received routine basic treatment,the control group was additionally treated with Lactulose,and the observation group was given modified Suoquan Pills on the basis of the control group,with a continuous treatment course of 4 cycles(7 days per cycle).The traditional Chinese medicine syndrome scores,clinical symptoms(defecation frequency,defecation duration per time,stool character)before and after treatment and the incidence of adverse reactions were compared between the two groups.Result:After treatment,the scores of dry and hard stool,difficult defecation,aversion to cold and cold limbs,soreness and weakness of waist and knees as well as the total score in the observation group were lower than those in the control group,the defecation frequency was more than that in the control group,the defecation duration per time was shorter than that in the control group,and the stool character was better than that in the control group,the incidence of adverse reactions during the treatment period was lower than that in the control group(P<0.05).Conclusion:Modified Suoquan Pills combined with Lactulose can effectively improve the traditional Chinese medicine syndromes and clinical symptoms of patients with constipation of kidney-Yang deficiency type,reduce the incidence of adverse reactions,and has high safety.

谢沐初;刘松明;刘官石生;张晓飞;刘歆;卢彦;李炳辉;杜家玮

赣州市中医院肛肠科 江西 赣州 341000赣县区中医院中医内科 江西 赣州 341000赣县区中医院中医内科 江西 赣州 341000赣州市中医院肛肠科 江西 赣州 341000赣州市中医院肛肠科 江西 赣州 341000赣州市中医院肛肠科 江西 赣州 341000赣州市中医院肛肠科 江西 赣州 341000赣州市中医院肛肠科 江西 赣州 341000

医药卫生

缩泉丸加味常规西医肾阳虚型便秘中医证候积分排便功能不良反应

Modified Suoquan PillsConventional western medicineConstipation of kidney-Yang deficiency typeTraditional Chinese medicine syndrome scoreDefecation functionAdverse reaction

《中国医学创新》 2026 (21)

41-45,5

2024年度江西省中医药科技计划项目(2024A0125)

10.3969/j.issn.1674-4985.2026.21.009

评论