首页|期刊导航|中国医学创新|LTG淋巴结清扫路径对肥胖胃癌患者手术情况、并发症及生活质量的影响

LTG淋巴结清扫路径对肥胖胃癌患者手术情况、并发症及生活质量的影响OA

The Impact of LTG Lymph Node Dissection Pathway on Surgical Outcomes,Complications,and Quality of Life in Obese Gastric Cancer Patients

中文摘要英文摘要

目的:探讨腹腔镜全胃切除术(laparoscopic total gastrectomy,LTG)中脾门优先清扫路径与传统中间入路清扫路径对肥胖胃癌患者术后并发症及生活质量的影响,为肥胖胃癌患者术式选择提供临床依据.方法:回顾性分析 2022 年 5 月—2025 年 5 月在九江市第一人民医院接受LTG治疗的 104 例肥胖胃癌患者的临床资料,根据淋巴结清扫路径分为观察组(脾门优先清扫,52 例)与对照组(传统中间入路清扫,52 例).比较两组手术相关指标(手术时间、术中出血量、淋巴结清扫数目)、术后并发症(吻合口瘘、腹腔出血、胰瘘、肺部感染等)发生率,评估术前及术后 3、6 个月生活质量.结果:观察组术中出血量显著少于对照组,第 10、11 组淋巴结清扫数目显著多于对照组(P<0.05);两组手术时间、总淋巴结清扫数目比较,差异无统计学意义(P>0.05).观察组术后并发症总发生率显著低于对照组,其中胰瘘发生率显著低于对照组(P<0.05);两组吻合口瘘、腹腔出血、肺部感染发生率比较,差异无统计学意义(P>0.05).术后 3、6 个月,观察组欧洲癌症研究与治疗组织生活质量核心量表(European Organization for Research and Treatment of Cancer quality of life questionnaire-core 30,EORTCQLQ-C30)中躯体功能、角色功能、情绪功能评分及胃癌特异性评价量表22项(quality of life questionnaire-stomach cancer 22,QLQ-STO22)中进食受限、焦虑症状评分均显著优于对照组(P<0.05).结论:在肥胖胃癌患者LTG中,脾门优先淋巴结清扫路径可减少术中出血,提高脾门区域淋巴结清扫彻底性,降低术后并发症发生率,且更利于术后生活质量恢复.

Objective:To investigate the effects of splenic gate priority dissection pathway versus traditional midline approach dissection pathway on postoperative complications and quality of life in obese gastric cancer patients undergoing laparoscopic total gastrectomy(LTG),providing clinical evidence for surgical strategy selection in obese gastric cancer patients.Method:A retrospective analysis was conducted on the clinical data of 104 obese gastric cancer patients treated with LTG from May 2022 to May 2025 in Jiujiang NO.1 People's Hospital.Patients were divided into an observation group(splenic gate priority dissection,n=52)and a control group(traditional midline approach dissection,n=52)based on lymph node dissection pathways.Surgical-related indicators(operational time,intraoperative blood loss,number of lymph nodes dissected)and postoperative complication rates(anastomotic leakage,intra-abdominal hemorrhage,pancreatic fistula,pulmonary infection,etc.)were compared between the two groups,quality of life was assessed before the operation and at 3 and 6 months postoperatively.Result:The observation group exhibited significantly less intraoperative blood loss than the control group,and significantly higher number of lymph nodes dissected in group 10 and group 11(P<0.05).No statistically significant differences were observed in operative time and total lymph node dissection numbers between the two groups(P>0.05).The observation group had significantly lower overall complication rates than the control group,with pancreatic fistula incidence being statistically significantly lower than the control group(P<0.05).No statistically significant differences were noted in the rates of anastomotic leakage,intra-abdominal hemorrhage,or pulmonary infection between the two groups(P>0.05).At 3 and 6 months postoperatively,the observation group demonstrated significantly better scores in physical function,role function,and emotional function of European Organization for Research and Treatment of Cancer quality of life questionnaire-core 30(EORTCQLQ-C30)as well as the scores for food restriction and anxiety symptoms in the quality of life questionnaire-stomach cancer 22(QLQ-STO22)compared to the control group(P<0.05).Conclusion:In obese gastric cancer patients undergoing LTG,the splenic gate priority lymph node dissection pathway reduces intraoperative bleeding,improves the thoroughness of splenic gate regional lymph node dissection,decreases postoperative complication rates,and facilitates better postoperative quality of life recovery.

周丽;丁鹏

九江市第一人民医院普外二科 江西 九江 332000九江市第一人民医院普外二科 江西 九江 332000

医药卫生

腹腔镜全胃切除术淋巴结清扫路径肥胖胃癌并发症生活质量

Laparoscopic total gastrectomyLymph node dissection pathwayObesityGastric cancerComplicationsQuality of life

《中国医学创新》 2026 (21)

26-31,6

江西省卫生健康委科技计划项目(202510774)

10.3969/j.issn.1674-4985.2026.21.006

评论