清热调血汤联合针刺治疗湿热瘀阻型子宫内膜异位症的临床效果OA
Clinical Effect of Qingre Tiaoxue Decoction Combined with Acupuncture in the Treatment of Endometriosis with Dampness-Heat Stagnant Type
目的:观察清热调血汤联合针刺治疗湿热瘀阻型子宫内膜异位症(endometriosis,EMT)的临床效果,以为该病的中西医结合治疗提供循证依据.方法:选取 2021 年 1 月—2025 年 4 月徐州市中医院收治的 126 例湿热瘀阻型EMT患者作为研究对象进行回顾性研究,根据治疗方法不同分为研究组和对照组,每组 63 例.对照组给予常规西药治疗,以 28 d为 1 个用药周期,连续治疗 3 个用药周期;研究组在对照组治疗基础上加用清热调血汤联合针刺治疗,连续治疗 3 个月经周期.比较两组临床疗效、不良反应发生率,以及治疗前后中医证候积分、VAS评分、血清炎症因子(IL-6、CRP)、盆腔病灶最大径及子宫体积.结果:治疗后,研究组中医证候积分[(8.23±2.15)分]低于对照组[(13.56±2.87)分],VAS评分[(2.15±0.68)分]低于对照组[(4.32±0.95)分](P<0.05).治疗后,研究组IL-6[(12.15±2.34)pg/mL]、CRP[(8.23±1.56)mg/L]水平低于对照组[(18.76±3.12)pg/mL、(13.56±2.18)mg/L](P<0.05).治疗后,研究组盆腔病灶最大径[(1.87±0.45)cm]小于对照组[(2.98±0.62)cm],子宫体积[(78.23±10.56)cm3]小于对照组[(95.68±12.34)cm3](P<0.05).研究组临床总有效率为 93.65%,高于对照组的 76.19%(P<0.05).研究组不良反应发生率为 6.35%(4/63),与对照组的 9.52%(6/63)比较,差异无统计学意义(P>0.05).结论:在常规西药治疗基础上,采用清热调血汤联合针刺治疗湿热瘀阻型EMT,可有效缓解患者疼痛症状,减轻炎症反应,缩小盆腔病灶及子宫体积,提升临床疗效,且安全性良好.
Objective:To observe the clinical effect of Qingre Tiaoxue Decoction combined with acupuncture in the treatment of endometriosis(EMT)with dampness-heat stagnant type,in order to provide evidence-based support for the treatment of this disease with integrated traditional Chinese and western medicine.Method:A retrospective study was conducted on 126 patients with EMT with dampness-heat stagnant type admitted to Xuzhou Hospital of Traditional Chinese Medicine from January 2021 to April 2025.They were divided into a study group and a control group according to different treatment methods,with 63 cases in each group.The control group was treated with conventional western medicine,taking 28 d as a medication cycle,the patients were treated for 3 consecutive medication cycles.The study group was treated with Qingre Tiaoxue Decoction combined with acupuncture on the basis of the treatment of the control group,for a total of 3 menstrual cycles.The clinical efficacy,incidence of adverse reactions,as well as traditional Chinese medicine syndromes scores,VAS scores,serum inflammatory factors(IL-6,CRP),maximum diameter of pelvic lesions and uterine volume before and after treatment were compared between the two groups.Result:After treatment,the traditional Chinese medicine syndromes score of the study group[(8.23±2.15)points]was lower than that of the control group[(13.56±2.87)points],and the VAS score[(2.15±0.68)points]was lower than that of the control group[(4.32±0.95)points](P<0.05).After treatment,the levels of IL-6[(12.15±2.34)pg/mL]and CRP[(8.23±1.56)mg/L]in the study group were lower than those in the control group[(18.76±3.12)pg/mL,(13.56±2.18)mg/L](P<0.05).After treatment,the maximum diameter of pelvic lesions in the study group[(1.87±0.45)cm]was smaller than that in the control group[(2.98±0.62)cm],and the uterine volume[(78.23±10.56)cm3]was smaller than that in the control group[(95.68±12.34)cm3](P<0.05).The overall clinical effective rate of the study group was 93.65％,which was higher than 76.19％of the control group(P<0.05).The incidence of adverse reactions in the study group was 6.35％(4/63),compared with 9.52％(6/63)in the control group,the difference was not statistically significant(P>0.05).Conclusion:On the basis of conventional western medicine treatment,the combination of Qingre Tiaoxue Decoction and acupuncture for EMT with dampness-heat stagnant type can effectively relieve the pain symptoms of patients,reduce inflammatory responses,shrink pelvic lesions and uterine volume,improve clinical efficacy,and has good safety.
王改;徐侠
徐州市中医院妇科 江苏 徐州 221003徐州市中医院妇科 江苏 徐州 221003
医药卫生
子宫内膜异位症清热调血汤针刺湿热瘀阻型炔雌醇环丙孕酮片
EndometriosisQingre Tiaoxue DecoctionAcupunctureDampness-heat stagnant typeEthinylestradiol and Cyproterone Acetate Tablets
《中国医学创新》 2026 (20)
34-39,6
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