内镜下黏膜剥离术与黏膜切除术治疗早期胃癌的效果与复发风险对比OA

Objective:To explore the clinical effects of endoscopic mucosal dissection and endoscopic mucosal resection in the treatment of early gastric cancer.Method:A prospective controlled study was conducted on 214 patients with early gastric cancer admitted to Jiangsu Shengze Hospital from January 2022 to January 2024.The patients were divided into the control group and the observation group by random number table method,with 107 cases in each group.The control group underwent endoscopic mucosal resection,while the observation group underwent endoscopic mucosal dissection.The therapeutic effects and prognosis of the two groups were compared.Result:The whole resection rate,complete resection rate and curative resection rate of the observation group were all higher than those of the control group,and the operation time was longer than that of the control group(P<0.05).The positive rate of horizontal resection margin after the operation and the rate of additional surgical operation in the observation group were lower than those in the control group(P<0.05).There were no statistically significant differences in the positive rate of vertical resection margin,vascular infiltration rate between the two groups(P>0.05).The VAS score 24 hours after the operation of the observation group was higher than that of the control group,and the hospital stay was longer than that of the control group(P<0.05).After 12 months of follow-up,the scores of each dimension of SF-36 in the observation group were higher than those in the control group,and the local recurrence rate was lower than that in the control group(P<0.05).Conclusion:For patients with early gastric cancer,endoscopic mucosal dissection is superior to endoscopic mucosal resection in achieving radical tumor resection,reducing the risk of recurrence,and improving prognosis,it is a better treatment option.