呼吸神经肌肉双相同步刺激对神经重症气管切开呼吸机依赖患者脱机的效果OA

Objective To explore the effect of respiratory neuromuscular biphasic synchronous stimulation on weaning from ventila-tor dependence in patients with severe neurological disorders undergoing tracheotomy. Methods From May,2023 to March,2025,94 critically ill patients with nerve related tracheostomy and ventilator depen-dence admitted to Zhengzhou Central Hospital Affiliated to Zhengzhou University were randomly divided into control group(n=47)and observation group(n=47).The control group received conventional treatment and comprehensive rehabilitation,while the observation group received respiratory nerve and muscle biphasic syn-chronous stimulation therapy on this basis.The oxygenation index(PaO2/FiO2),diaphragm mobility,diaphragm thickening rate,maximum inspiratory pressure(MIP),maximum expiratory pressure(MEP),mechanical ventila-tion time and weaning success rate were compared before,and two and four weeks after treatment. Results Three cases in the control group and one in the observation group were dropped out.There was no significant difference in various indicators between two groups before treatment(P>0.05).Two and four weeks after treat-ment,PaO2/FiO2,diaphragm movement,diaphragm thickening rate,MIP and MEP improved with the prolonga-tion of time in both groups(F>23.632,P<0.001),and they were better in the observation group than in the con-trol group(P<0.05).The mechanical ventilation time was shorter(t=2.287,P<0.05)and the success rate of weaning was higher(χ2=4.622,P<0.05)in the observation group than in the control group. Conclusion The respiratory neuromuscular biphasic synchronous stimulation can be applied to patients with severe neu-rological conditions who are dependent on tracheotomy ventilators,to accelerate the recovery of respiratory mus-cle strength,shorten the duration of mechanical ventilation,and increase the success rate of weaning from the ventilator.