RNF26 bridges ER stress and autophagy in the clearance of MERS envelope proteinOA
RNF26 bridges ER stress and autophagy in the clearance of MERS envelope protein
Ziyue Li;Yang Wang;Jingbo Qie;Shuangqu Li;Zhaobing Gao;Hin Chu;Bingqing Xia
School of Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing 210046,China||CAS Key Laboratory of Receptor Research,State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China||University of Chinese Academy of Sciences,Beijing 100049,ChinaState Key Laboratory of Emerging Infectious Diseases,Department of Microbiology,School of Clinical Medicine,Li Ka Shing Faculty of Medicine,The University of Hong Kong,and Pandemics Research Alliance Unit at the University of Hong Kong,Hong Kong Special Administrative Region,ChinaShanghai Fifth People's Hospital and Institutes of Biomedical Sciences,Fudan University,Shanghai 200032,ChinaCAS Key Laboratory of Receptor Research,State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,ChinaSchool of Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing 210046,China||CAS Key Laboratory of Receptor Research,State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China||University of Chinese Academy of Sciences,Beijing 100049,ChinaState Key Laboratory of Emerging Infectious Diseases,Department of Microbiology,School of Clinical Medicine,Li Ka Shing Faculty of Medicine,The University of Hong Kong,and Pandemics Research Alliance Unit at the University of Hong Kong,Hong Kong Special Administrative Region,China||Centre for Virology,Vaccinology and Therapeutics,Hong Kong Science and Technology Park,Hong Kong Special Administrative Region,China||Materials Innovation Institute for Life Sciences and Energy(MILES),HKU-SIRI,Shenzhen 518000,ChinaCAS Key Laboratory of Receptor Research,State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China||University of Chinese Academy of Sciences,Beijing 100049,China
Coronavirus envelope(E)proteinsAutophagyHost-virus interactionCellular stress responsePathogenicity
Coronavirus envelope(E)proteinsAutophagyHost-virus interactionCellular stress responsePathogenicity
《中国病毒学》 2026 (3)
612-623,12
We are grateful to the National Natural Science Foundation of China(82341058,92169202),the Scientific Instrument Developing Project of the Chinese Academy of Sciences(PTYQ2024YZ0008),Fund of Shanghai Science and Technology(20ZR1474200,22QA1411000),Fund of Shanghai Sailing Program(23YF1433100),Fund of Youth Innovation Promotion Association(Grants 2023078),Youth Inno the Science and Technology Commission of Shanghai Municipality(23JC1404300),and the National Key R&D Program of China(2023YFC2307800).Hin Chu acknowledges support from the Prevention and Control of Emerging and Major Infectious Diseases-National Science and Technology Major Proj-ect(2026ZD01911200 and 2026ZD01911201)the Health and Medical Research Fund(COVID1903010-14,23220522,CID-HKU1-5),Food and Health Bureau,The Government of the Hong Kong Special Administrative Regionthe General Research Fund(17118621,17119122),Collabora-tive Research Fund(C7103-22G),and Theme-Based Research Scheme(T11-709/21-N),Research Grants Council of the Hong Kong Special Administrative Regionthe InnoHK initiative of the Innovation and Technology Commission of the Hong Kong Special Administrative Region Governmentthe National Key Research and Development Program of China(2021YFC0866100 and 2023YFC3041600)the General Pro-gramme of the Guangdong Provincial Natural Science Foundation,China(2023A1515012325,2023A1515011891)and support from Dr.Gallant Ho under the Gallant Ho Outstanding Young Professorship.
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