Age-related pharyngeal microbiome and host transcriptomic signatures underlying fever responses in RSV bronchiolitisOA
Age-related pharyngeal microbiome and host transcriptomic signatures underlying fever responses in RSV bronchiolitis
Ying Li;Yan Li;Yamin Sun;Xiaoxia Lu;Di Liu;Yi Yan;Jingyuan Zhang;Haizhou Liu;Muhammad Noman;Muhammad Arif Rizwan;Ismaila Damilare Isiaka;Hebin Chen;Wenqing Li;Nan Zhao
State Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan 430071,China||University of Chinese Academy of Sciences,Beijing 101409,China||Department of Respiratory Medicine,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China||Pediatric Respiratory Disease Laboratory,Institute of Maternal and Child Health,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,ChinaDepartment of Respiratory Medicine,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China||Pediatric Respiratory Disease Laboratory,Institute of Maternal and Child Health,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China||Department of Pathogen Biology,School of Basic Medicine,Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,ChinaNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases,Beijing Ditan Hospital,Capital Medical University,Beijing 101409,ChinaDepartment of Respiratory Medicine,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China||Pediatric Respiratory Disease Laboratory,Institute of Maternal and Child Health,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,ChinaState Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan 430071,China||University of Chinese Academy of Sciences,Beijing 101409,ChinaDepartment of Respiratory Medicine,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China||Pediatric Respiratory Disease Laboratory,Institute of Maternal and Child Health,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,ChinaDepartment of Respiratory Medicine,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China||Pediatric Respiratory Disease Laboratory,Institute of Maternal and Child Health,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,ChinaState Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan 430071,ChinaState Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan 430071,China||University of Chinese Academy of Sciences,Beijing 101409,ChinaState Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan 430071,China||University of Chinese Academy of Sciences,Beijing 101409,ChinaState Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan 430071,China||University of Chinese Academy of Sciences,Beijing 101409,ChinaDepartment of Respiratory Medicine,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China||Pediatric Respiratory Disease Laboratory,Institute of Maternal and Child Health,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,ChinaDepartment of Respiratory Medicine,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China||Pediatric Respiratory Disease Laboratory,Institute of Maternal and Child Health,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,ChinaDepartment of Respiratory Medicine,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China||Pediatric Respiratory Disease Laboratory,Institute of Maternal and Child Health,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China
Respiratory syncytial virus(RSV)BronchiolitisAge-dependentFeverHost responseAirway microbiome
Respiratory syncytial virus(RSV)BronchiolitisAge-dependentFeverHost responseAirway microbiome
《中国病毒学》 2026 (3)
574-585,12
This study was supported by the National Natural Science Foundation of China(32500045,82550120),Natural Science Foundation of Wuhan(2026020301040160),Medical Research Project of Wuhan Health Com-mission(WX23A90),the Natural Science Foundation of Hubei Province(2026AFB683,2021CFA012,2023AFB221),the Funding for Scientific Research Projects from Health Commission of Hubei Province(WJ2021M262),and the Funding for Scientific Research Project from Wuhan Children's Hospital(2024FEBSJJ007,2025FEBSHJJ003).
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