无症状脑梗死中医体质与危险因素相关性研究OA

Objective It is to explore the etiology,constitution distribution characteristics of traditional Chinese medi-cine and the correlation between risk factors and constitution in patients with silent brain infarction(SBI),and to provide new ideas for the prevention and treatment of SBI with traditional Chinese medicine.Methods A total of 220 patients diag-nosed as SBI based on cranial CT scans conducted at the Health Examination Center of Henan Provincial Hospital of Tradi-tional Chinese Medicine from December 2021 to January 2024 were included in the study.Their clinical data was collected through questionnaires,and their emotions and constitutions were identified by the Seven Emotions Rating Scale and the standards outlined in Classification and Determination of Constitution of Traditional Chinese Medicine.The constitution-re-lated risk factors were screened out by Chi-square tests and multivariate logistic regression analysis.Results Among the SBI patients,anger was the predominant emotional factor contributing to the disease,accounting for 60 cases(27.3%);in terms of dietary habits,102 patients(46.4%)had a preference for fatty and sweet foods,and in terms of physical activity,131 patients(59.5%)lacked exercise;in terms of constitution distribution,189 cases(85.9%)had imbalanced consti-tutions,in which phlegm-dampness and Qi-deficiency were the two most common constitutions.Univariate analysis revealed that gender,age,drinking,and the comorbidities including hypertension,diabetes,hyperlipidemia and carotid atheroscle-rosis were all significantly associated with the TCM constitution of SBI patients(all P<0.05).Multivariate logistic regres-sion analysis showed that drinking,comorbidities including hypertension,hyperlipidemia and carotid atherosclerosis were independent risk factors for the SBI patients with phlegm-dampness constitution(all P<0.05,OR>1),while gender was a protective factor for the SBI patients with phlegm-dampness constitution(P<0.05,OR<1);gender,concomitant diabe-tes,and concomitant carotid atherosclerosis were independent risk factors for the SBI patients with Qi-deficiency constitution(all P<0.05,OR>1).Conclusion The TCM etiology of SBI is characterized by the interplay of"deficiency,phlegm,and stasis",phlegm dampness and Qi-deficiency are the susceptible constitutions.The occurrence of phlegm dampness constitution is related to drinking,hypertension,hyperlipidemia and other factors,while that of Qi-deficiency constitution is related to gender,diabetes and carotid atherosclerosis.Individualized intervention measures should be formulated according to the characteristics of TCM constitution distribution of SBI in clinic,so as to improve the prognosis of SBI patients.