黑水虻昆虫蛋白对断奶仔猪肠道健康的影响OA

Black soldier fly(Hermetia illucens)has shown broad application potential in animal production due to its high protein content,rich functional nutritional value,and high rearing efficiency.This paper sys-tematically reviews and analyzes recent advances regarding the effects of black soldier fly insect protein on the intestinal mechanical barrier,immune barrier,and microbial barrier in weaned piglets.The available evi-dence indicates that black soldier fly protein can maintain the integrity of the mechanical barrier by increas-ing villus height and upregulating the expression of tight-junction proteins.It can enhance mucosal immune defense by modulating cytokine secretion and increasing mucosal sIgA levels;and it can optimize the intesti-nal microbial community by promoting the proliferation of beneficial bacteria and inhibiting the growth of pathogenic bacteria,thereby significantly reducing the incidence of diarrhea in weaned piglets.In addition,this paper discusses the synergistic mechanisms of key bioactive components in black soldier fly,including lauric acid,antimicrobial peptides,and chitin,in maintaining intestinal health,and further outlines the major challenges for practical application.Overall,this review aims to provide a scientific ref-erence for the rational use of black soldier fly insect protein in piglet diets.