基于微生态调控的抑菌防脱洗发水功效及其头皮健康影响研究OA

The efficacy of a shampoo formulated with a plant-derived anti-hair-loss extract and the anti-dandruff agent 846 Plus on hair loss and scalp microbiota was evaluated.A 12-week intervention study was conducted in 24 subjects experiencing hair loss.The results showed that hair shedding count decreased significantly by 43.7%,scalp hydration increased by up to 85.5%,and scalp sebum content decreased by 9.37%after shampoo use.High-throughput sequencing analysis revealed that the shampoo significantly increased the diversity of the scalp microbiota and reduced the relative abundance of microorganisms associated with hair shedding.Specifically,the relative abundance of Malassezia restricta decreased from 61.81%to 48.64%,while that of Staphylococcus decreased from 21.58%to 9.10%.These findings suggest that the shampoo may alleviate hair loss by improving the scalp microenvironment and restoring microbial homeostasis.