超声在肝细胞癌消融疗效评估中的应用与进展OA

Accurate assessment of treatment response after local ablation is of great importance for detecting residual viable tumor,evaluating ablative margins,and guiding subsequent follow-up and monitoring in patients with hepatocellular carcinoma(HCC).Contrast-enhanced computed tomography and magnetic resonance imaging are currently the main imaging modalities for post-ablation evaluation,but have certain limitations in real-time imaging,intraoperative application,and repeatability.Ultrasound,especially contrast-enhanced ultrasound(CEUS),can be used throughout the entire process of ablation therapy for HCC due to its advantages of real-time visualization of microvascular perfusion,no ionizing radiation,and repeatability,thereby playing an important role in detecting residual viable tumor,assessing immediate treatment response,and monitoring patients during follow-up.This article reviews the pathological basis and major endpoints of treatment response assessment after thermal ablation for HCC,with a focus on the clinical application of ultrasound techniques and the Contrast-Enhanced Ultrasound Liver Imaging Reporting and Data System Treatment Response Algorithm.In addition,it discusses the future development directions of multimodal imaging,quantitative assessment,and standardized evaluation,in order to provide a reference for further optimizing the treatment response assessment system for HCC after ablation.