超声在肝细胞癌早期诊断与鉴别诊断中的应用策略OA
Strategies for the application of ultrasound in early and differential diagnosis of hepatocellular carcinoma
肝细胞癌起病隐匿,早期诊断和准确鉴别对改善患者预后具有重要意义.超声因便捷、实时、可重复及适于动态随访,仍是肝细胞癌高危人群筛查和初步评估的重要影像学方法.近年来,随着相关超声技术的发展,超声在肝细胞癌中的应用已由单纯病灶检出逐步拓展至病灶定性、鉴别诊断和预后评估等.本文将结合肝细胞癌早期诊断与鉴别诊断的临床需求,对灰阶超声、多普勒超声及超声造影在肝细胞癌中的应用价值、临床定位及局限进行综述,重点讨论其在小肝细胞癌中的评估和常见鉴别诊断中的作用,强调应结合背景肝状态、病灶形态、血流特征、增强方式及随访动态变化进行综合判断,以提高肝细胞癌的早期诊断和鉴别诊断水平.
Hepatocellular carcinoma(HCC)often has an insidious onset,and early diagnosis and accurate differential diagnosis are critical for improving the prognosis of patients.Ultrasound remains an important radiological examination for the screening and initial assessment of high-risk populations due to its advantages of convenience,real-time monitoring,repeatability,and suitability for dynamic follow-up.With the development of ultrasound technologies in recent years,the application of ultrasound in HCC has gradually expanded from lesion detection to lesion characterization,differential diagnosis,and prognostic evaluation.With reference to the clinical needs for the early and differential diagnosis of HCC,this article reviews the application value,clinical localization,and limitations of gray-scale ultrasound,Doppler ultrasound,and contrast-enhanced ultrasound in HCC,with a focus on their application in the evaluation and differential diagnosis of small HCC.It highlights that comprehensive evaluation should be performed based on liver background,lesion morphology,blood flow features,enhancement patterns,and dynamic changes during follow-up,so as to improve the early and differential diagnosis of HCC.
胡嘉薇;罗渝昆
中国人民解放军总医院第一医学中心超声诊断科,北京 100853中国人民解放军总医院第一医学中心超声诊断科,北京 100853
癌,肝细胞超声检查诊断
Carcinoma,HepatocellularUltrasonographyDiagnosis
《临床肝胆病杂志》 2026 (7)
1501-1506,6
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