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吕文亮基于"主客浑受"分期辨治幽门螺杆菌胃炎经验OA

Lyu Wenliang's experience in staged syndrome differentiation and treatment of Helicobacter pylori gastritis based on the theory of"intertwining of host and pathogens"

中文摘要英文摘要

"主客浑受"出自《湿热条辨》,为脾虚复感湿热之邪,继而邪气深入厥阴血脉所致.吕文亮基于"主客浑受"理论分期辨治幽门螺杆菌(Hp)胃炎,认为该病的基本病机为正气亏虚、湿热内蕴、气滞血瘀,治疗上主张以祛邪、扶正、透邪为原则.早期治疗以辛开苦降、调和气机为主;中期治疗以活血通络、祛瘀解毒为主;后期治疗以清养胃阴、扶正祛邪为主.临证时辨证论治灵活运用半夏泻心汤、连朴清幽汤、沙参麦冬汤等进行加减化裁,通过分期治疗和辨证施治,有效改善患者症状.

"Intertwining of host and pathogens"originates from the Treatise on Differentiation and Treatment of Damp-Heat Diseases,referring to the pathological state of spleen deficiency complicated with damp-heat,which then penetrates into the Jueyin meridian.Professor Lyu Wenliang applies the theory to the staged syndrome differentiation and treatment of Helicobacter pylori gastritis.He holds that the fundamental pathogeneses of this disease lie in vital qi deficiency,damp-heat retention,and qi stagnation with blood stasis.His treatment principles are focused on eliminating pathogenic factors,strengthening the body's resistance,and expelling pathogenic factors.In the early stage,his treatment is centered on acrid opening and bitter descending to regulate qi movement;in the middle stage,his treatment focuses on activating blood circulation to unblock collaterals and removing stasis to detoxify;and in the late stage,his treatment emphasizes nourishing stomach yin and reinforcing the body's resistance while eliminating pathogenic factors.In clinical practice,he flexibly applies and modifies formulas such as Banxia Xiexin Decoction,Lianpo Qingyou Decoction,and Shashen Maidong Decoction based on the patients'specific syndromes and physical conditions.Through staged treatment and syndrome differentiation,Lyu Wenliang usually improves patients'symptoms effectively.

孟昊阳;吕文亮;黄超群

湖北中医药大学中医学院,武汉 430061||湖北中医药大学疫病研究所,武汉 430061湖北中医药大学中医学院,武汉 430061||湖北中医药大学疫病研究所,武汉 430061湖北省中医院/湖北中医药大学附属医院,武汉 430061||湖北时珍实验室,武汉 430065

医药卫生

Hp胃炎主客浑受《湿热条辨》吕文亮

Helicobacter pylori gastritisintertwining of host and pathogenTreatise on Differentiation and Treatment of Damp-Heat DiseasesLyu Wenliang

《吉林中医药》 2026 (8)

985-990,6

国家自然科学基金项目(82505321)第七批全国老中医药专家学术经验继承工作项目(国中医药人教函[2022]76号)湖北省中医药管理局资助项目(ZY2025M030)湖北省科学技术厅自然科学基金项目(2023AFB347)

10.13463/j.cnki.jlzyy.2026.08.008

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