Pien Tze Huang exerts anti-tumor effect by promoting CSF-1R degradation and cleavage in tumor-associated macrophagesOA
Pien Tze Huang exerts anti-tumor effect by promoting CSF-1R degradation and cleavage in tumor-associated macrophages
Jun-Jie Zhang;Han-Shi Guo;Jing-Na Yuan;Si-Yu Chen;Bei Li;Shi-Cong Wang;Chun-Dong Yu;Yi-Lin Hong
Xiamen Key Laboratory of Traditional Chinese Medicine Bio-engineering,School of Pharmacy,Xiamen Medical College,Fujian 361023,China||State Key Laboratory of Cellular Stress Biology,Innovation Center for Cell Biology,School of Life Sciences,Xiamen University,Fujian 361104,ChinaState Key Laboratory of Cellular Stress Biology,Innovation Center for Cell Biology,School of Life Sciences,Xiamen University,Fujian 361104,ChinaState Key Laboratory of Cellular Stress Biology,Innovation Center for Cell Biology,School of Life Sciences,Xiamen University,Fujian 361104,ChinaCollege of Traditional Chinese Medicine,Fujian University of Traditional Chinese Medicine,Fujian 350122,ChinaOrdos Center for Disease Control and Prevention,Ordos,Inner Mongolia Autonomous Region 017010,ChinaFujian Pien Tze Huang Enterprise Key Laboratory of Natural Medicine Research and Development,Fujian 363000,ChinaState Key Laboratory of Cellular Stress Biology,Innovation Center for Cell Biology,School of Life Sciences,Xiamen University,Fujian 361104,ChinaXiamen Key Laboratory of Traditional Chinese Medicine Bio-engineering,School of Pharmacy,Xiamen Medical College,Fujian 361023,China||State Key Laboratory of Cellular Stress Biology,Innovation Center for Cell Biology,School of Life Sciences,Xiamen University,Fujian 361104,China
Pien Tze Huangcolorectal cancertumor-associated macrophagesCSF-1RTLR2-iRhom2-ADAM17immunotherapy
Pien Tze Huangcolorectal cancertumor-associated macrophagesCSF-1RTLR2-iRhom2-ADAM17immunotherapy
《传统医学研究（英文版）》 2026 (11)
14-26,13
This study received funding from the Natural Science Foundation of Fujian Province of China(No.2025J083282023J01249),the Natural Science Foundation of Xiamen Municipality(No.3502Z202571070),and Zhangzhou Pien Tze Huang Pharmaceutical Co.Ltd(No.YHT-21036-N-2102).
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