首页|期刊导航|CT理论与应用研究|超高分辨力CT对中耳胆脂瘤骨质破坏诊断效能的验证

超高分辨力CT对中耳胆脂瘤骨质破坏诊断效能的验证OA

Diagnostic Performance of Ultra-high-resolution CT for Detecting Bone Destruction in Middle Ear Cholesteatoma

中文摘要英文摘要

目的:探讨超高分辨力 CT(U-HRCT)对中耳胆脂瘤引起耳内结构骨质破坏的显示能力与术中表现的对照研究结果,并从手术角度分析其临床效能.方法:回顾性分析 2024年 2月至 2026年 2月病理证实的 60例中耳胆脂瘤患者,术前均行 U-HRCT检查.计算 U-HRCT的敏感性、特异性、阳性预测值(PPV)、阴性预测值(NPV)、符合率和 Kappa值,将影像表现与术中表现进行比较.结果:U-HRCT在检测鼓室盾板、鼓室盖、锤骨、砧骨及半规管壁骨质破坏方面的敏感性均超过 90%.其中:半规管壁破坏的显示与术中结果完全一致(k=1);鼓室盾板、鼓室盖、锤骨等骨质破坏的显示与术中结果高度一致(k>0.8);砧骨、镫骨及面神经管等骨质破坏的显示与术中结果亦表现为良好的一致性(k值>0.6).结论:U-HRCT可精准评估中耳胆脂瘤引发的听小骨、面神经管等结构的骨质破坏,有助于外科医生术前发现潜在的危险情况.

Objective:Middle ear cholesteatoma is a potentially destructive non-neoplastic lesion that erodes the adjacent bony structures and may lead to intraotologic and intracranial complications.This study evaluated the performance of ultra-high-resolution computed tomography(U-HRCT)in visualizing the bony destruction of intraotologic structures caused by middle ear cholesteatoma,using intraoperative findings as the reference standard,and to analyze its clinical efficacy from a surgical perspective.Methods:A retrospective analysis was performed on the data from 60 patients who were pathologically diagnosed with middle ear cholesteatoma at our hospital between February 2024 and February 2026.All the patients underwent preoperative U-HRCT.The imaging findings were compared with the intraoperative observations,and the sensitivity,specificity,positive predictive value(PPV),negative predictive value(NPV),accuracy,and kappa value of U-HRCT were calculated.Results:The sensitivity of U-HRCT for detecting the bony destruction of the scutum,tegmen tympani,malleus,incus,and semicircular canal wall was greater than 90%in all cases.Its identification of the destruction of the semicircular canal wall agreed perfectly with the intraoperative results(k=1).The detection of the bony erosion involving the scutum,tegmen tympani,and malleus showed excellent consistency with the intraoperative findings(k>0.8),whereas that of the erosion of the incus,stapes,and facial nerve canal achieved good consistency(k>0.6).Conclusion:U-HRCT enables an accurate preoperative assessment of the bony destruction of the ossicles,facial nerve canal,and other structures caused by middle ear cholesteatoma and can assist surgeons in identifying potential high-risk conditions before surgery.

杨佳佳;钟业鸣;钱波;嵇洪波;车子刚

东南大学医学院附属南京同仁医院医学影像科,南京 211102东南大学医学院附属南京同仁医院医学影像科,南京 211102东南大学医学院附属南京同仁医院医学影像科,南京 211102东南大学医学院附属南京同仁医院医学影像科,南京 211102东南大学医学院附属南京同仁医院医学影像科,南京 211102

医药卫生

超高分辨力CT中耳胆脂瘤听小骨面神经管

ultra-high-resolution CTmiddle ear cholesteatomaauditory ossiclesfacial nerve canal

《CT理论与应用研究》 2026 (5)

869-874,6

北京市科技计划项目(耳鼻喉双源锥形束计算机体层摄影设备示范应用(Z241100009024020))北京市自然科学基金面上项目(基于U-HRCT的耳科手术面神经损伤风险智能预警关键技术研究(7252281))国家自然科学基金面上项目(基于医学知识介导的中耳病变超高分辨力CT智能判读关键技术研究(62371316)).

10.15953/j.ctta.2026.158

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