数值模拟在中药制剂现代制造中的应用OA
Application of numerical simulation in modern manufacturing of traditional Chinese medicine preparations
中医药现代化发展战略实施以来,数值模拟已成为研究中药制造过程的重要技术手段.利用计算机对制药过程中的复杂物理现象和相关设备开展仿真分析,有助于优化工艺参数、改进设备和提升产品质量.该文系统综述了近 10 年来数值模拟在丸剂、片剂、胶囊剂、颗粒剂及液体制剂制造中的应用情况,进而探讨了其在中药制剂应用中存在的现实问题,并提出相应的发展建议,以期推动该技术与中药制造体系更深入融合,助力中药产业高质量发展.
Since the implementation of the development strategy for traditional Chinese medicine(TCM)modernization,numerical simulation has become a vital technical tool for studying TCM manufacturing processes.Using computers to simulate and analyze complex physical phenomena and related equipment in pharmaceutical production contributes to optimizing process parameters,improving equipment performance,and enhancing product quality.This paper systematically reviews the application of numerical simulation in the manufacturing of pills,tablets,capsules,granules,and liquid formulations over the past decade.Furthermore,it discusses practical challenges in its application and offers corresponding development suggestions.The aim is to promote deeper integration of numerical simulation into the TCM manufacturing system and support high-quality development of the TCM industry.
宋戈;于洋;李正
天津中医药大学 中药制药工程学院,天津 301617||省部共建组分中药国家重点实验室,天津 301617天津中医药大学 中药制药工程学院,天津 301617||省部共建组分中药国家重点实验室,天津 301617||现代中药创新全国重点实验室,天津 301617天津中医药大学 中药制药工程学院,天津 301617||省部共建组分中药国家重点实验室,天津 301617||现代中药创新全国重点实验室,天津 301617||现代中医药海河实验室,天津 301617||天津市中药智能制药与绿色制药重点实验室,天津 301617
数值模拟仿真中药制剂制备工艺中药制造
numerical simulationsimulationTCM preparationspreparation processTCM manufacturing
《中国中药杂志》 2026 (16)
4537-4544,8
工业和信息化部2024年重点专项(2440STCZB2617)
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