多环境任务下单眼弱视患者的眼动特征及视觉功能评估OA

Objective To evaluate the eye movement characteristics of patients with monocular amblyopia under different visual environments and task conditions.Methods Eleven patients with monocular amblyopia(22 eyes)and 17 healthy controls(34 eyes)were enrolled in this study.Eye movement parameters during reading,free viewing,and smooth pursuit tasks were recorded using an Eyelink 1000 Plus eye tracker.Results In the reading task,compared with the control group,the amblyopia group exhibited significantly shorter fixation duration within the region of interest(ROI),fewer fixation counts,and a lower proportion of fixations allocated to the ROI for both eyes(P＜0.05 to P＜0.001).In the free viewing task,the amblyopia group had longer mean fixation duration than controls(simple environment:P＜0.01;complex environment:P＜0.05),and the magnitude of change in fixation duration in response to environmental shifts was significantly greater in the amblyopia group(P＜0.05).In the smooth pursuit task,the mean distance between the fixation point and the target point was larger in the amblyopia group(slow speed:P＜0.01;fast speed:P＜0.001 to P＜0.01),with a significantly greater difference in tracking distance when the target speed changed(P＜0.01).Conclusions Both static and dynamic visual functions are impaired in patients with monocular amblyopia compared with healthy individuals,and this intergroup deficit is exacerbated with increasing task difficulty.