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腔镜甲状腺手术30年:技术演进、现状与思考OA

Endoscopic thyroidectomy over the past 30 years:technical evolution,current status,and reflections

中文摘要英文摘要

腔镜甲状腺手术在过去30年间经历了由颈前小切口视频辅助技术逐步发展为经胸前/乳晕、经腋窝、经腋乳联合等远程入路,并进一步发展至经口腔前庭入路及机器人平台辅助技术.现有研究结果表明,在严格掌握适应证、由接受规范化培训的团队于高手术量中心开展的前提下,腔镜甲状腺手术的总体并发症发生率(包括喉返神经损伤、低钙血症、血肿等)与开放手术相比差异无统计学意义;但手术时间延长、医疗费用增加、学习曲线较长及入路特异性并发症,仍是限制其临床推广的关键因素.远程入路的主要优势在于颈部无可见瘢痕,但该优势并不等同于组织创伤程度更低;经口腔前庭入路虽可实现体表无瘢痕并提供居中对称的术野,但亦伴随口腔污染、颏神经损伤等新发并发症风险;机器人手术平台虽显著改善了术野清晰度及主刀医师的操作自由度,但仍面临成本效益比及医疗资源可及性等方面的挑战.未来研究应由单纯的"入路创新"转向以医疗质量管理为核心,进一步明确腔镜甲状腺手术在长期肿瘤学结局,嗓音、吞咽、感觉等功能结局,病人报告结局及卫生经济学评价方面的循证依据.中国具备病例规模、技术路径及共识体系等优势,下一阶段应进一步推动分层准入管理、建立全国性注册登记数据库及开展多中心前瞻性研究,使腔镜甲状腺手术的临床实践始终锚定于安全性、功能保护与肿瘤学获益.

Over the past three decades,endoscopic thyroid surgery has evolved from minimally invasive video-assisted thyroidectomy through a range of remote-access procedures,including anterior chest/areolar,transaxillary,and bilateral axillo-breast approaches,to the transoral vestibular approach and robotic platform-assisted techniques.Existing research indicates that,with strict patient selection,standardized training,and performance in high-volume centers,the overall incidence of major complications,including recurrent laryngeal nerve injury,hypocalcemia,and postoperative hematoma,shows no statistically significant differences compared with conventional open surgery.However,prolonged operative time,increased costs,a substantial learning curve,and approach-specific complications remain key factors limiting its clinical adoption.The primary advantage of remote-access procedures is the avoidance of a visible cervical scar,but this does not necessarily indicate reduced overall tissue trauma.The transoral endoscopic thyroidectomy vestibular approach offers a truly scarless option with a symmetric midline view,but is also associated with new complications such as oral contamination and mental nerve injury.Robotic platforms significantly improve visualization and instrument dexterity for the primary surgeon,yet their wider adoption is constrained by cost-effectiveness and accessibility challenges.Future research should shift from mere"approach innovation"to a quality management-centric focus,further clarifying the evidence for endoscopic thyroid surgery in long-term oncologic outcomes,functional outcomes(voice,swallowing,sensation),patient-reported outcomes(PROs),and health economic evaluations.Leveraging its large case volume,diverse technical pathways,and evolving consensus system,China is well positioned to promote stratified access management,establish a national registry database,and conduct multicenter prospective studies,thereby ensuring that the clinical practice of endoscopic thyroid surgery remains anchored in safety,functional preservation,and oncologic benefit.

王平;谢秋萍;徐逢雨

浙江大学医学院附属第二医院甲状腺外科,浙江 杭州 310009浙江大学医学院附属第二医院甲状腺外科,浙江 杭州 310009浙江大学医学院附属第二医院甲状腺外科,浙江 杭州 310009

医药卫生

腔镜甲状腺手术远程入路经口腔前庭入路机器人甲状腺手术

endoscopic thyroid surgeryremote-access approachtransoral vestibular approachrobotic thyroid surgery

《中国实用外科杂志》 2026 (6)

754-760,7

National Natural Science Foundation of China,Young Scientists Fund(No.82303597) 国家自然科学基金青年基金项目(No.82303597)

10.19538/j.cjps.issn1005-2208.2026.06.07

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