静脉血栓栓塞症预防与治疗湖南专家共识OA

Venous thromboembolism(VTE)is a major preventable cause of morbidity and mortality among hospitalized patients.Although several national guidelines have established general principles for the prevention and management of VTE,practical recommendations for many clinical scenarios remain insufficient,particularly regarding anticoagulation strategies for special thrombotic conditions,timing of ambulation,indications for inferior vena cava filter(IVCF)placement,and interventional therapies.To address these issues and meet regional clinical needs,the Hunan VTE Prevention and Control Alliance and the Special Committee of Thrombosis and Hemostatic Drugs of the Hunan Pharmacological Society convened a multidisciplinary expert panel to develop this consensus.The consensus was formulated in accordance with guideline-development standards using the GRADE approach and a modified Delphi process.A total of 12 key clinical questions were identified,and 30 recommendations were developed,covering VTE prevention,risk assessment,D-dimer application,pharmacological and mechanical prophylaxis,anticoagulation management for special thrombotic conditions,ambulation strategies,IVCF use,and interventional treatment.This consensus aims to provide evidence-based and practice-oriented recommendations for healthcare professionals across Hunan Province,promote standardized VTE management,and facilitate the establishment of a homogeneous regional VTE prevention and treatment system.