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经皮穴位电刺激对胃肠道肿瘤患者术后胃肠功能影响的Meta分析OA

The Effect of Transcutaneous Electrical Acupoint Stimulation on Postoperative Gastrointestinal Function in Patients with Gastrointestinal Cancer:A Meta-Analysis

中文摘要英文摘要

目的 通过系统评价与荟萃分析了解经皮穴位电刺激(TEAS)对胃肠道肿瘤患者术后胃肠功能的影响.方法 检索数据库包括PubMed、Cochrane Library、EMBASE、中国知网、万方数据库,收集2000年1月至2025年6月关于经皮穴位电刺激对胃肠道肿瘤患者术后胃肠功能影响的随机对照试验.采用Cochrane偏倚风险工具评价纳入研究的方法学质量,使用STATA SE软件进行荟萃分析,并通过敏感性分析、漏斗图评估结果稳健性与发表偏倚.结果 共纳入26项合格研究,涉及2529例受试者.分析显示,TEAS显著缩短患者术后首次排便时间(标准均数差(SMD)=-1.01,95%置信区间(CI):-1.35至-0.66,P<0.001)、首次排气时间(SMD=-1.57,95%CI:-1.97至-1.17,P<0.001)、首次肠鸣音恢复时间(SMD=-1.02,95%CI:-2.05至-0.98,P<0.001),并降低术后恶心呕吐发生率(比值比:0.29,95%CI:0.20至0.41,P<0.001).敏感性分析表明,逐一剔除任何单项研究后结果仍保持稳定.漏斗图及Egger检验未发现显著发表偏倚.结论 TEAS可辅助促进胃肠道肿瘤患者术后胃肠功能恢复,可为临床提供参考.

Objective:To understand the effect of transcutaneous acupoint electrical stimulation(TEAS)on gastrointestinal function of patients with gastrointestinal tumor after operation through systematic review and meta-analysis.Methods:The retrieval databases include PubMed、Cochrane Library、EMBASE、China HowNet and Wanfang Database,and the ran-domized controlled trials on the effect of transcutaneous acupoint electrical stimulation on postoperative gastrointestinal function of patients with gastrointestinal tumors from January 2000 to June 2025 were collected.Cochrane bias risk tool was used to evaluate the methodological quality of the included research,and STATA SE software was used for meta-a-nalysis.Sensitivity analysis and funnel chart were used to evaluate the robustness and publication bias of the results.Re-sults:A total of 26 qualified studies involving 2529 subjects were included.The analysis showed that TEAS significantly shortened the first defecation time(standard mean difference(SMD)=-1.01,95%confidence interval(CI):-1.35 to-0.66,P<0.001)and the first exhaust time(SMD=-1.57,95%CI:-1.97 to-).95%CI:-2.05 to-0.98,P<0.001),and reduced the incidence of postoperative nausea and vomiting(odds ratio:0.29,95%CI:0.20 to 0.41,P<0.001).Sensitivity analysis showed that the results remained stable after excluding any single study one by one.No signifi-cant publication bias was found in funnel plot and Egger test.Conclusion:TEAS can help promote the recovery of gastroin-testinal function in patients with colorectal cancer after operation,which can provide reference for clinic.

洪晓芸;吴赞

中山大学肿瘤防治中心肠胃科,广东 广州 510275中山大学肿瘤防治中心肠胃科,广东 广州 510275

医药卫生

胃肠道肿瘤术后胃肠功能经皮穴位电刺激荟萃分析系统评价

Gastrointestinal cancerPostoperative gastrointestinal functionTranscutaneous electrical acupoint stimulation(TEAS)Meta-analysisSystematic review

《生命科学仪器》 2026 (4)

25-28,4

10.11967/2026240809

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