牙髓再生治疗在年轻恒牙慢性根尖周炎中的临床应用OA

Objective:To compare the clinical efficacy of pulp regeneration therapy versus apexification in the treat-ment of chronic periapical periodontitis involving immature permanent teeth.Methods:A total of 40 pediatric patients(with 40 affected immature permanent teeth)diagnosed with chronic periapical periodontitis who were admitted to our hospital from March 2024 to March 2025 were enrolled.Based on the principle of informed consent obtained from the guardians,the pa-tients were divided into two groups:the experimental group(22 teeth)received pulp regeneration therapy,while the control group(18 teeth)received apexification.All patients were followed up for 12 months postoperatively.Changes in root develop-ment,root canal wall thickness,and root length of the affected teeth were observed and compared between the two groups.Re-sults:The increases in root canal wall thickness and root length in the experimental group were statistically significant com-pared with those in the control group(P<0.05).Root development in the pulp regeneration therapy group was significantly superior to that in the apexification group,and the difference was statistically significant(P<0.05).Conclusion:In the clini-cal management of chronic periapical periodontitis in immature permanent teeth,pulp regeneration therapy is more effective than apexification in promoting continued root development.