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深度学习在脑肿瘤MRI图像诊断中的研究进展OA

Research Progress of Deep Learning in MRI Image Diagnosis of Brain Tumors

中文摘要英文摘要

脑肿瘤作为高致死性神经系统疾病,精准诊断是改善预后的关键.传统影像学诊断在微小病灶识别、异质性刻画及定量分析方面存在局限,而深度学习技术为突破此类局限提供了重要技术支撑.围绕深度学习在脑肿瘤诊断的研究与应用展开系统综述.梳理当前广泛使用的脑肿瘤公共数据集,归纳核心评价指标及其临床意义.聚焦三大核心任务:在肿瘤检测方面,从两阶段与单阶段技术路线梳理;在肿瘤分割领域,围绕二维切片、三维体素及多对比度序列归纳;在肿瘤分类任务中,从单网络与多网络模型维度剖析,系统梳理主流方法的技术演进,总结了不同技术路线的核心特征,旨在明确当前的技术现状与发展方向,并探讨大语言模型在各项任务中的融合策略与应用前景.评述深度学习模型在临床辅助诊断中的转化应用现状,剖析其面临的核心挑战,展望其临床转化路径.总结现有方法的局限性,从数据、模型优化及临床应用三个层面提出未来研究的重点方向.

Brain tumors are highly fatal neurological diseases,for which precise diagnosis is crucial to improving prognosis.Traditional imaging techniques are often limited in detecting small lesions,characterizing tumor heterogeneity,and facilitating quantitative analysis.Deep learning technology provides crucial technical support for overcoming such limitations.This paper systematically reviews deep learning research and applications in brain tumor diagnosis.Firstly,widely used public datasets are summarized,and key evaluation metrics along with their clinical significance are outlined.Secondly,the review focuses on three core tasks.For tumor detection,it systematically compares two-stage and one-stage approaches.For tumor segmentation,it summarizes methods based on 2D slices,3D volumes,and multi-contrast sequences.For tumor classification,it analyzes models from single-network and multi-network architectural perspectives.The evolution of mainstream methods is traced,the defining characteristics of different technical routes are highlighted,and the integration strategies and application prospects of large language models in these domains are discussed.Furthermore,the current status of clinical translation for deep learning models is evaluated.Core challenges are analyzed,and potential pathways toward clinical adoption are outlined.Finally,limitations of existing methods are summarized.Future research directions are proposed from three perspectives:data,model improvement,and clinical application.

苏菲;马素芬;生慧;蔡肖红;郭英慧;魏国辉;李小童;徐晟杰

山东中医药大学 医学信息工程学院,济南 250355山东中医药大学 医学信息工程学院,济南 250355||山东中医药大学 教务处,济南 250355山东中医药大学 医学信息工程学院,济南 250355山东中医药大学 医学信息工程学院,济南 250355山东中医药大学 医学院,济南 250355山东中医药大学 医学信息工程学院,济南 250355山东中医药大学 医学信息工程学院,济南 250355山东中医药大学 医学信息工程学院,济南 250355

信息技术与安全科学

深度学习脑肿瘤核磁共振图像目标检测肿瘤分割肿瘤分类

deep learningbrain tumormagnetic resonance imagingobject detectiontumor segmentationtumor classification

《计算机科学与探索》 2026 (8)

2184-2205,22

国家自然科学基金(82074293)山东省自然科学基金面上项目(ZR2022MH203)山东省中医药科技项目(2020M005)山东省研究生教育教学改革研究项目(SDYJSJGC2024063)山东中医药大学科学研究基金项目(KYRW2024M02)山东中医药大学2025年第一批横向科研项目(JWC2024-042). This work was supported by the National Natural Science Foundation of China(82074293),the General Project of Natural Science Foundation of Shandong Province(ZR2022MH203),the Traditional Chinese Medicine Technology Project of Shandong Province(2020M005),the Postgraduate Education and Teaching Reform Research Project of Shandong Province(SDYJSJGC2024063),the Sci-entific Research Fund of Shandong University of Traditional Chinese Medicine(KYRW2024M02),and the First Batch of Horizontal Scientific Research Projects of Shandong University of Traditional Chinese Medicine in 2025(JWC2024-042).

10.3778/j.issn.1673-9418.2508070

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