多组学视角下微藻对环境响应机制的研究进展OA

As dominant primary producers in aquatic ecosystems,microalgae exhibit population-and communi-ty-level dynamics that are highly sensitive to environmental changes,rendering them crucial bioindicators of eco-logical shifts.While traditional research methodologies remain limited in elucidating the molecular mechanisms underlying microalgal responses,the rapid evolution of"omics"technologies offers powerful tools for probing in-tricate adaptations to environmental fluctuations,particularly extreme conditions such as low temperatures.The molecular responses of microalgae to environmental stressors encompass multilayered processes,including gene-expression regulation,functional-level proteomic alterations,and metabolic remodeling.Omics methods pro-vide multidimensional insights into these mechanisms,clarifying how microalgae cope with environmental stresses.This thesis reviews recent technological advances in genomics,transcriptomics,proteomics,and metabolomics for studying microalgal environmental responses,encompassing physiological processes,interspecific associations,and community-level structural dynamics.Furthermore,it summarizes and prospects for future trajectories of omics research.Such studies should likely focus on integrating multi-omics data to construct systematic models spanning from genotype to phenotype.These integrative approaches are essential for accurately and comprehensively eluci-dating molecular regulatory networks that govern microalgal adaptation to environmental changes.