基于"中虚血积"理论辨治三阴性乳腺癌OA
Treatment based on syndrome differentiation of triple-negative breast cancer based on the theory of middle Jiao deficiency and blood stasis
三阴性乳腺癌是乳腺癌中预后较差的亚型,患者多为化疗或术后人群,病情复杂,治疗难度大."中虚血积"是三阴性乳腺癌的核心病机,中焦脾胃亏虚后,生化乏源,阳气不振,气机郁滞,进而导致痰凝、血瘀、毒邪互结,形成有形之积,终致乳腺癌发生与进展.治疗上,强调培中固本、温阳化浊以扶正,疏肝益肾、调和冲任以调脏,化痰散瘀、解毒通络以祛邪,注重标本兼顾、攻补有序.为中医药治疗三阴性乳腺癌提供新的思路.
Triple-negative breast cancer(TNBC)is a subtype of breast cancer with a relatively poor prognosis,primarily affecting patients undergoing chemotherapy or postoperative care,characterized by complex conditions and challenging treatment.This article proposes that"middle Jiao deficiency and blood stasis"is the core pathogenesis of TNBC.It is believed that after the deficiency of the spleen and stomach in middle Jiao,the source of biochemical transformation becomes insufficient,yang qi fails to flourish,and qi movement becomes stagnant,leading to the mutual binding of phlegm coagulation,blood stasis,and toxic pathogens,forming tangible accumulations,ultimately resulting in the occurrence and progression of breast cancer.In terms of treatment,it emphasizes strengthening the foundation and reinforcing the body,warming yang to resolve turbidity for supporting healthy qi;soothing the liver and tonifying the kidneys,harmonizing the thoroughfare and conception vessels for regulating visceral functions;resolving phlegm and dispersing stasis,detoxifying and unblocking collaterals for eliminating pathogens.And it focuses on addressing both manifestation and root cause,with the balanced approach of attacking and tonifying,providing new insights for traditional Chinese medicine in treating TNBC.
张文风;邓国梁;崔巍
长春中医药大学基础医学院,长春 130117长春中医药大学基础医学院,长春 130117长春中医药大学基础医学院,长春 130117
医药卫生
中虚血积三阴性乳腺癌辨证论治
middle Jiao deficiency and blood stasistriple-negative breast cancertreatment based on syndrome differentiation
《长春中医药大学学报》 2026 (8)
887-890,4
吉林省科技发展计划项目(YDZJ202601ZYTS521)
评论