灭螨醌在柑橘上的残留降解及膳食风险评估OA

To address the lack of data on the residual degradation dynamics and dietary intake risk of acequinocyl 15%EW on citrus fruits,field residue tests were carried out using orah,shatangju,and kumquat as test materials.A high-performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS)method was used to determine the residual degradation dynamics of acequinocyl and hydroxyacequinocyl in different citrus varieties,and a dietary risk assessment was conducted.The results showed that acequinocyl and hydroxyacequinocyl exhibited good linear relationships(R2>0.99)in different citrus matrices.The limits of detection were 1.7-3.9 μg/kg and 1.0-1.2 μg/kg,respectively;the limits of quantitation were 4.5-7.9 μg/kg and 2.0-3.2 μg/kg,respectively;the recoveries were 79.4%—90.4%and 79.5%—92.6%,respectively,with RSD values of 2.4%—9.2%and 2.0%—9.0%,respectively.Except for the pulp of Shatangju,the degradation patterns of the two compounds in other parts of the three citrus varieties conformed to first-order kinetics,with half-lives of 17.5-24.8 d and 20.0-43.3 d,respectively.On the 14th and 28th days after application,the total residues of acequinocyl in the whole fruit of the three citrus varieties were 0.042-0.077 mg/kg and 0.013-0.046 mg/kg,respectively.The chronic and acute dietary exposure risks for all age groups were 0.03%—0.78%and 0.19%—2.84%,respectively.This study provides basic data for the rational use of acequinocyl on citrus and the establishment of maximum residue limits.