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Anogenital human papillomavirus infection patterns by anatomical site and sexual orientation in Chinese men:a national multi-center studyOA

中文摘要

Human papillomavirus(HPV)is the most prevalent sexually transmitted infection worldwide1.More than 200 HPV genotypes have been identified and are classified as high-risk HPV(HR-HPV)or low-risk HPV(LR-HPV)according to their oncogenic potential.Persistent infection with HR-HPV is associated with cancers of the cervix,vagina,vulva,anus,penis,and oropharynx.In contrast,LR-HPV infections cause benign lesions,such as genital warts and recurrent respiratory papillomatosis.

Shangying Hu;Huan Yang;Jinyu Zhang;Hongyang Yu;Yutong Li;Douhong Li;Qiaoyun Du;Yu Cui;Xuelian Zhao;Yongjiang Liu;Fanghui Zhao

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,ChinaNational Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,ChinaNational Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,ChinaBeijing Health Guard Biotechnology Inc.,Beijing 100176,ChinaNational Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China School of Population Medicine and Public Health,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,ChinaBeijing Health Guard Biotechnology Inc.,Beijing 100176,ChinaNational Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China School of Public Health,Lanzhou University,Lanzhou 730000,ChinaNational Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,ChinaNational Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,ChinaBeijing Health Guard Biotechnology Inc.,Beijing 100176,ChinaNational Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China

医药卫生

genital wartsanatomical sitesexual orientationsexually transmitted infectionhuman papillomavirus infectionbenign lesionssuchhuman papillomavirus hpvrecurrent respiratory papillomatosis

《Cancer Biology & Medicine》 2026 (7)

P.1044-1050,7

supported by the National Natural Science Foundation of China(Grant No.81773533)。

10.20892/j.issn.2095-3941.2026.0129

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