“CLINICAL-BFR”:An exploratory blood flow restriction protocol focusing on clinical applicationOA
Purpose:Traditional blood flow restriction resistance training(BFR-Trad)is a cost-effective and time-efficient exercise modality that offers significant skeletal muscle benefits,including strength and mass gains.Despite employing low loads,BFR-Trad may not be well tolerated by all populations due to its high intensity,painassociated muscle discomfort,low affectivity,and cardiovascular responses.Consequently,reducing BFR intensity may be an interesting approach to making traditional BFR more clinically applicable.This was approached through the proposal of the present Clinical BFR.Methods:Twenty-two healthy,untrained subjects(both female and male)aged between 18 and 30 years participated.Subjects completed three sessions of unilateral knee extension exercises randomly assigned to the BFR-Trad,BFR-Clinical_c(cadenced),and BFR-Clinical_a(-autoregulated)exercise protocols.Results:The BFR-Trad condition induced greater increases in perceived exertion,discomfort,delayed onset muscle soreness(DOMS),and lactate levels compared to the BFR-Clinical conditions(p<0.05).Muscle concentric velocity showed greater increases in the BFR-Clinical_a condition(p<0.001),along with higher affectivity ratings for the exercise compared to the BFR-Clinical_c and BFR-Trad conditions(p<0.05).Conclusion:Compared to traditional BFR,clinical BFR was scored as less intense,reduced pain-associated discomfort,decreased DOMS,increased affectivity,diminished systolic blood pressure responses,decreased fatigue and muscle activation,and promoted similar glycemic responses.Altogether,our results support the potential use of clinical BFR in clinical settings.
Fabricio Eduardo Rossi;Kassiana de Araújo Pessôa;Zhi Xia;Jakob Lauver;Daniel Newmire;Jason Michael Cholewa;Steven Machek;Mario Alves de Siqueira Filho;Fabio Santos Lira;Antonio Herbert Lancha-Jr;Emilia Zawieja;Nelo Eidy Zanchi
Immunometabolism of Skeletal Muscle and Exercise Research Group,Department of Physical Education,School of Technology and Sciences,São Paulo State University(UNESP),Presidente Prudente,SP,Brazil Professor at Graduate Program in Movement Science-Interunit,São Paulo State University(UNESP),Presidente Prudente,SP,BrazilLaboratory of Skeletal Muscle Biology and Human Strength Performance(LABFORCEH),Federal University of Maranhão(UFMA),São Luís,MA,BrazilExercise Physiology and Biochemistry Laboratory,College of Physical Education and Health,Wenzhou University,Wenzhou,ChinaDepartment of Kinesiology,Coastal Carolina University,Conway,SC,USASchool of Health Promotion and Kinesiology,Texas Woman''s University,Denton,TX,USADepartment of Exercise Physiology,College of Health Sciences,University of Lynchburg,USAKinesiology Department,College of Health Sciences and Human Services,California State University-Monterey Bay,Seaside,CA,USADepartment of Physical Education,Federal University of Maranhão(UFMA),São Luís,MA,BrazilExercise and Immunometabolism Research Group,Department of Physical Education,School of Technology and Sciences,São Paulo State University(UNESP),Presidente Prudente,SP,Brazil Centro de Investigação em Desporto e Atividade Física(CIDAF),University of Coímbra,Coímbra,PortugalLaboratory of clinical investigation:experimental surgery,LIM26,Hospital das Clínicas,Faculdade de Medicina,University of São Paulo,BrazilDepartment of Human Nutrition and Dietetics,Poznan University of Life Sciences,PolandLaboratory of Skeletal Muscle Biology and Human Strength Performance(LABFORCEH),Federal University of Maranhão(UFMA),São Luís,MA,Brazil
社会科学
Resistance trainingBlood flow restrictionMuscle powerDiscomfortMuscle fatigue
《Sports Medicine and Health Science》 2026 (5)
P.583-592,10
Fabricio Eduardo Rossi would like to thank Conselho Nacional de Desenvolvimento Científico e Tecnològico-CNPq(Funding validity by March/2023 to March/2026)for their support.Nelo Eidy Zanchi would like to thank Fundação de Amparo a Pesquisa do Estado do Maranhão(FAPEMA),Process Number:UNIVERSAL-06660/22,for their support.
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