Changes of pupil parameters and visual quality after cataract surgery as well as their correlationOA
●AIM:To compare the changes of pupil parameters and visual quality after cataract surgery and explore their potential correlations.●METHODS:This retrospective cohort study analyzed clinical data of Han Chinese patients who received cataract surgery from June 2016 to October 2016.Visual acuity,pupil size,pupil shift,wavefront aberrations,point spread function(PSF),and modulation transfer function(MTF)were detected preoperatively,1d and 1mo postoperatively.Pupil parameters and visual outcomes were compared across the three time points.●RESULTS:A total of 110 eyes from 110 patients(42 males and 68 females)were enrolled,with a mean age of 66.8±7.9y(range:53–88y).Under both photopic and mesopic conditions,pupil diameter and pupil shift at 1d and 1mo after surgery were significantly lower than baseline levels.Corneal aberrations decreased postoperatively.Photopic and mesopic modulation transfer function derived from higher-order(HO)aberrations increased significantly from postoperative day 1 to postoperative month 1.Pupil size was positively correlated with wavefront aberrations,and negatively correlated with total PSF and HO-PSF.Significant correlations were identified between preoperative pupil diameter and 1-month postoperative visual quality indicators(including aberrations,PSF and modulation transfer function).A preoperative mesopic pupil diameter over 5.60 mm effectively predicted poor 1-month postoperative visual quality(HO aberrations>0.5μm),with an area under the curve(AUC)of 0.71.●CONCLUSION:Pupil parameters and visual quality alter significantly after cataract surgery,and moderate correlations exist between pupil diameter and visual quality at each time point.Preoperative pupil diameter is correlated with 1-month postoperative visual quality.
Fan Yang;Jie Xu;Pei-Min Lin;Ming-Yang Wang;Tian-Yu Zheng
Eye Institute and Department of Ophthalmology,Eye&ENT Hospital,Fudan University,Shanghai 200031,China NHC Key Laboratory of Myopia and Related Eye Diseases,Shanghai 200031,China Shanghai Key Laboratory of Visual Impairment and Restoration,Shanghai 200031,ChinaEye Institute and Department of Ophthalmology,Eye&ENT Hospital,Fudan University,Shanghai 200031,China NHC Key Laboratory of Myopia and Related Eye Diseases,Shanghai 200031,China Shanghai Key Laboratory of Visual Impairment and Restoration,Shanghai 200031,ChinaEye Institute and Department of Ophthalmology,Eye&ENT Hospital,Fudan University,Shanghai 200031,China NHC Key Laboratory of Myopia and Related Eye Diseases,Shanghai 200031,China Shanghai Key Laboratory of Visual Impairment and Restoration,Shanghai 200031,ChinaDepartment of Ophthalmology,Shanghai Tenth People’s Hospital,Shanghai 200072,China Visual Rehabilitation Center,Tongji University School of Medicine,Shanghai 200072,China Tongji Eye Institute,Tongji University School of Medicine,Shanghai 200072,ChinaDepartment of Ophthalmology,Shanghai Tenth People’s Hospital,Shanghai 200072,China Visual Rehabilitation Center,Tongji University School of Medicine,Shanghai 200072,China Tongji Eye Institute,Tongji University School of Medicine,Shanghai 200072,China
医药卫生
a b e r r a t i o n sc a t a r a c t s u r g e r ymodulation transfer functionpoint spread functionpupil diameter
《International Journal of Ophthalmology(English edition)》 2026 (8)
P.1518-1525,8
Supported by National Natural Science Foundation of China(No.81300747)Natural Science Foundation of Shanghai(Science and Technology Commission of Shanghai Municipality,No.22ZR1410400No.19ZR1408600)the Excellent Young Doctor Training Program of Shanghai(Shanghai Municipal Health Commission,No.2015-2018)the Clinical Research Project of Shanghai Municipal Health Commission(Shanghai Municipal Health Commission,No.202540103)the Shanghai Municipal Health Commission’s Seed Program for Medical New Technology Research and Translation(Shanghai Municipal Health Commission,No.2025ZZ2068)the Scientific Research Program of Shanghai Pudong New Area Health Commission(Shanghai Pudong New Area Health Commission,No.PW2024D-05)Young Clinical Scientist Training Program(Fudan University Shanghai Medical College,No.DGF828019-2/038)the“Medicine+X”Interdisciplinary Research Project(Tongji University,No.2025-0553-YB-07)Vision and Action-Ophthalmology Clinical Research Support Program(the Bethune Foundation,No.BFC-KECS-LC-20251022-01)Shanghai Tenth People’s Hospital Undergraduate Teaching Courses(Tenth People’s Hospital of Tongji University,Funding Type:A:2025 Blended Teaching Courses and B:2025 Demonstration Courses).
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