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Effect of active vision therapy on contrast sensitivity in bilateral amblyopiaOA

中文摘要

●AIM:To evaluate the effectiveness of combining patching with active vision therapy,compared to patching with placebo training on contrast sensitivity(CS)in pediatric participants with bilateral refractive amblyopia.●METHODS:In this double-blind,clinical trial,43 participants aged 5–8 with bilateral refractive amblyopia,unresponsive to spectacles,were randomly assigned to either the experimental group(active vision therapy plus patching)or the control group(placebo treatment with patching)for four months.Active therapy included antisuppression,accommodative,vergence,and visual memory exercises.CS was measured at baseline and after four months,serving as key outcome measures.●RESULTS:Forty participants(20 in each group)completed the study.The mean age for the experimental group(5 males)was 6.10±0.84y,and 6.50±1.15y for the control group(11 males).CS in the experimental group improved by 0.10 log(right eye),0.14 log(left eye),and 0.07 log binocularly(P≤0.03).The control group showed no statistically significant enhancements in monocular or binocular CS(P≥0.07).Compared to the control group,the experimental group demonstrated a rate of change in monocular CS of 0.05 during follow-up time.●CONCLUSION:Active vision therapy leads to significant and accelerates improvements in CS among children with bilateral refractive amblyopia.

Saeed Rahmani;Saeedeh Hoseinmenni;Cirous Dehghani;Ebrahim Jafarzadehpour;HalehKangari;Jeffery Cooper;Mohammad Reza Talebnejad;Ali Reza Akbarzadeh Baghban;Enayatollah Osroosh

Department of Optometry,School of Rehabilitation Sciences,Shahid Beheshti University of Medical Sciences,Tehran 16169-13111,IranDepartment of Optometry,School of Rehabilitation Sciences,Shahid Beheshti University of Medical Sciences,Tehran 16169-13111,IranDiscipline of Optometry and Vision Science,University of Canberra,ACT 2617,AustraliaDepartment of Optometry,School of Rehabilitation Sciences,Iran University of Medical Sciences,Tehran 14496-14535,IranDepartment of Optometry,School of Rehabilitation Sciences,Shahid Beheshti University of Medical Sciences,Tehran 16169-13111,IranSUNY College of Optometry,New York,NY 10036,USAPoostchi Ophthalmology Research Center,Department of Ophthalmology,School of Medicine,Shiraz University of Medical Sciences,Shiraz 71348-45794,IranProteomics Research Center,Department of Biostatistics,School of Allied Medical Sciences,Shahid Beheshti University of Medical Sciences,Tehran 19716-53313,IranDepartment of Optometry,School of Rehabilitation Sciences,Shahid Beheshti University of Medical Sciences,Tehran 16169-13111,Iran

医药卫生

active vision therapybilateral refractive amblyopiacontrast sensitivitychildren

《International Journal of Ophthalmology(English edition)》 2026 (8)

P.1550-1555,6

10.18240/ijo.2026.08.13

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