Integrated drug management for elderly patients with congestive heart failure:enhancing medication accuracy using the MINE(Medicine IN gEriatric)applicationOA
Background This study evaluated the impact of the Medicine IN Geriatric(MINE)application,which integrates the Integrated Medicine Management(IMM)model and STOPP/START criteria,on improving prescribing practices in elderly patients with congestive heart failure(CHF).Methods A two-phase study was conducted:validation of the IMM model and its implementation via the MINE app.A quasiexperimental pretest-posttest control group design was used in a hospital in East Kalimantan,Indonesia.Patients aged 60-79 years were randomly assigned to the intervention or control group.The intervention group received IMM-based pharmaceutical services,including medication reconciliation,repeated medication reviews,and individualized discharge counseling.The outcomes assessed included polypharmacy rates,potentially inappropriate medications(PIMs),potential prescribing omissions(PPOs),and health-related quality of life,using the EQ-5D-5L and EQ-VAS tools.Results Expert validation showed high content validity,with I-CVI≥0.86 and S-CVI=0.94.During implementation,the use of antiplatelets,statins,angiotensin converting enzyme inhibitors(ACEI),and angiotensin receptorβ-blockers(ARB)declined from admission to discharge.PIMs,such as beta-blockers in patients with conduction disorders and ACE-I/ARBs in those with hyperkalemia,also decreased.The intervention group''s EQ-5D-5L scores improved from 0.552 to 0.664,whereas the control group''s scores declined slightly.EQ-VAS scores also increased significantly in the intervention group.Conclusion The MINE-based IMM intervention effectively reduced inappropriate prescribing and enhanced the quality of life in elderly patients with CHF.This technology-enabled multidisciplinary approach supports safer prescribing in geriatric care.
Welinda Dyah Ayu;Umi Athiyah;Carta Agrawanto Gunawan;Elida Zairina
Doctoral Program in Pharmaceutical Sciences,Faculty of Pharmacy,Universitas Airlangga,Surabaya,Indonesia Departemen of Clinical Pharmacy,Faculty of Pharmacy,Mulawarman University,Samarinda,IndonesiaDepartment of Pharmacy Practice,Faculty of Pharmacy,Universitas Airlangga,Surabaya,Indonesia Innovative Pharmacy Practice and Integrated Outcome Research(INACORE)Group,Faculty of Pharmacy,Universitas Airlangga,Surabaya,IndonesiaInternal medicine specialist doctor,RSUD Abdoel Wahab Sjahranie,Samarinda,IndonesiaDepartment of Pharmacy Practice,Faculty of Pharmacy,Universitas Airlangga,Surabaya,Indonesia Innovative Pharmacy Practice and Integrated Outcome Research(INACORE)Group,Faculty of Pharmacy,Universitas Airlangga,Surabaya,Indonesia Center of Excellence for Patient Safety and Quality,Universitas Airlangga,Surabaya,Indonesia
医药卫生
improving prescribing practicescongestive heart failure chf methodsintegrated medicine management imm modelMedicine Geriatric ApplicationElderly PatientsIntegrated Drug ManagementSTOPP START CriteriaPrescribing Practices
《Journal of Geriatric Cardiology》 2026 (5)
P.296-308,13
supported by DRPM PDD 2023-2024,Ministry of Research,Technology and Higher Education of Indonesia(No.040/E5/PG.02.00.PL/20241675/B/UN3.LPPM/PT.01.03/2024)。
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