Advances in surgical management of restrictive strabismus in thyroidassociated orbitopathyOA
Recent advances in the surgical management of restrictive strabismus caused by thyroid-associated orbitopathy(TAO)demonstrate a clear trend toward precision and individualization.This review synthesizes current literature,highlighting innovations in preoperative evaluation,surgical techniques,and outcome assessment over the past decade.Preoperative assessment has evolved from clinical observation alone to a comprehensive model incorporating serological markers and highresolution imaging,significantly improving the accuracy of surgical timing decisions.Surgical techniques have been refined to address a range of complex scenarios,enhancing predictability,success rates while reducing reoperation rates.Outcome measures now prioritize functional vision and patient-reported outcomes alongside ocular alignment.Furthermore,emerging therapies,including biologics,offer novel non-surgical options for active-phase disease management and perioperative care.Based on the evidence synthesized herein,the field is moving toward a more personalized approach;however,high-level prospective trials evaluating surgical strategies remain limited.Surgeons are encouraged to base decisions on comprehensive assessments to optimize functional and quality-of-life outcomes.Future directions may involve the integrating evolving biologic therapies with advanced data analytics,an approach that holds promise for further personalization.
Yiwen Zeng;Hongru Chen;Jingjing Liu;Zhuoma Gesang;Te Zhang;Huasheng Yang;Huijing Ye
State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangdong Provincial Clinical Research Center for Ocular Diseases,Guangzhou 510060,ChinaState Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangdong Provincial Clinical Research Center for Ocular Diseases,Guangzhou 510060,ChinaState Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangdong Provincial Clinical Research Center for Ocular Diseases,Guangzhou 510060,ChinaState Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangdong Provincial Clinical Research Center for Ocular Diseases,Guangzhou 510060,ChinaState Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangdong Provincial Clinical Research Center for Ocular Diseases,Guangzhou 510060,ChinaState Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangdong Provincial Clinical Research Center for Ocular Diseases,Guangzhou 510060,ChinaState Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangdong Provincial Clinical Research Center for Ocular Diseases,Guangzhou 510060,China
医药卫生
thyroid-associated orbitopathyrestrictive strabismusstrabismus surgery
《Eye Science》 2026 (2)
P.101-114,14
supported by Science and Technology Program of Guangzhou,China(SL2023A03J00480)the National Natural Science Foundation of China(82371099)Clinical High-tech and Major Technology Projects in Guangzhou(2024P-GX13)General Program of Natural Science Foundation of Guangdong Province(2026A1515011922).
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